Self-assembling nanoparticles of dually hydrophobic prodrugs constructed from camptothecin analogue for cancer therapyDually hydrophobic prodrugsSelf-assembly mechanismReductive -responsiveCamptothecin analogueES-285Nanomedicines have shown success in cancer therapy in recent years because of their excellent ...
Self-assembling peptide nanoparticles (SAPN) incorporating T-cell epitopes and displaying the P domain of the norovirus protein VP1 are described. The nanoparticles of the invention consist of aggregates of a continuous peptide chain comprising two coiled coil oligomerization domains connected by a ...
SELF-ASSEMBLING NANOPARTICLES COMPOSED OF TRANSME
Self-assembling nanoparticles for intra-articular delivery of anti-inflammatory proteins Intra-articular delivery of therapeutics to modulate osteoarthritis (OA) is challenging. Delivery of interleukin-1 receptor antagonist (IL-1Ra), the natura... RE Whitmire,DS Wilson,A Singh,... - 《Biomaterials》...
©2006ElsevierB.V.Allrightsreserved.Keywords:Thiol-functionalizedpoly(St-co-AA)nanospheres;Goldnanoparticles;HRP;Biosensors;Self-assembly1.IntroductionBiosensorsareanalyticaldevicesorbiosensingsystemsinwhichabiologicalcomponentspecificallyrecognizesandbindsthetargetanalyte.Ingeneral,biosensorsconsistoftwocom-ponents:...
InAs∕ZnSecore/shell nanoparticles (NP) were self-assembled on GaAs substrates using different organic molecules of varying length and properties as linker... Y Paltiel,A Aharoni,U Banin,... - 《Applied Physics Letters》 被引量: 26发表: 2006年 Designed Self-assembling Peptide Nanobiomaterials Th...
Immunoabsorbent nanoparticles based on a tobamovirus displaying protein A. Earlier attempts to express peptides longer than 20 aa on the surface of tobamoviruses such as tobacco mosaic virus have failed. Surprisingly, we found tha... S Werner,S Marillonnet,G Hause,... - 《Proceedings of the...
Self‐Assembling Stereocomplex Nanoparticles by Enantiomeric Poly(γ‐glutamic acid)‐poly(lactide) Graft Copolymers as a Protein Delivery Carrier Amphiphilic graft copolymers, poly(-glutamic acid)-graft-poly(lactide) (-PGA-g-PLA) bearing pendent poly(L-lactide) (PLLA) or poly(D-lactide) (PDLA) ...
Collectively, C 16 -3RP nanoparticles show promising biocompatibility and in vivo therapeutic efficacy without apparent resistance development. These advancements may facilitate the development of peptide-based antibiotics in clinical settings. 展开 关键词: mechanism of action in vivo efficacy stability ...
(PBS). Average size and size distribution of the RGD-TRAIL-ELP nanoparticles were then characterized using Dynamic Light Scattering (DLS; DynaPro Plate Reader, Wyatt Technology) over a range of temperature. The light scattering data were analyzed using a regularization fit and the Rayleigh spheres ...