Status epilepticusFDG-PETDiffusion tensor imagingWe describe a patient with chronic pharmacoresistant epilepsy related to right parietal focal cortical dysplasia (FCD), who became seizure-free following an episode of convulsive status epilepticus (SE). Magnetic resonance imaging (MRI) and fludeoxyglucose...
Epilepsy is not well controlled by current anti-seizure drugs (ASDs). High mobility group box 1 (HMGB1) is a DNA-binding protein in the nucleus regulating transcriptional activity and maintaining chromatin structure and DNA repair. In epileptic brains, H
Cerebral hypoperfusion has been proposed as a potential cause of postictal neurological dysfunction in epilepsy, but its underlying mechanism is still unclear. We show that a 30% reduction in postictal cerebral blood flow (CBF) has two contributing factors: the early hypoperfusion up to ∼30 min...
Convulsions vs. Seizures Lesson Summary Frequently Asked Questions What could cause convulsions? Factors that can cause convulsions include epilepsy, brain injuries like trauma or strokes, infections such as encephalitis, genetic conditions, and even high temperatures in young children. These factors can ...
Many adolescents with undiagnosed focal epilepsy seek evaluation in emergency departments (EDs). Accurate history-taking is essential to prompt diagnosis and treatment. In this study, we investigated ED recognition of motor vs nonmotor s... J Nora,F Monica,Jacob,PellinenHadley T.,GreenwoodDennis J...
Status epilepticus after stroke. Stroke. 2001;32(5):1169–72. Article CAS PubMed Google Scholar Fisher RS, van Emde BW, Blume W, Elger C, Genton P, Lee P, Engel Jr J. Epileptic seizures and epilepsy: definitions proposed by the International League Against Epilepsy (ILAE) and the ...
A total of 13 drug-resistant patients (6 men, mean age 32.8 years, range 22–63 years) with different types of partial epilepsy were selected (Supplementary Table 1). SEEG electrodes were implanted in the regions suspected to be in the epileptogenic zone. Each electrode had 10–15 contacts ...
Psychogenic non-epileptic seizures (PNES), also known as pseudoseizures are events superficially resembling an epileptic seizure, but without the characteristic electrical discharges associated with epilepsy. Psychogenic nonepileptic seizures are paroxysmal episodes that resemble and are often misdiagnosed as ...
Seizure-type were tonic–clonic (n = 13), generalized (n = 5), status epilepticus (n = 6), grand mal (n = 2), or not reported (n = 13). Twelve patients had a history of epilepsy, in 15 patients takotsubo cardiomyopathy–associated seizure was the first or the information was not...
Focal status epilepticus 1 (2) 1 (3) 0 0 0 Generalized convulsive status epilepticus 2 (4) 2 (6) 0 0 0 Seizures types in patients with autoimmune-associated epilepsy, n (%), multiple answers possible Focal seizures with/without impaired awareness 5 (10) 1 (3) 1 (7) 3 (60) 0 Fo...