This decision analytic study uses a simulation model to evaluate the trade-offs associated with 4 treatment strategies based on primary vs secondary
World Federation of Societies of Biological Psychiatry (WFSBP) guidelines for biological treatment of unipolar depressive disorders, part 1: Acute and continuation treatment of major depressive disorder 2002, World Journal of Biological Psychiatry Transcranial magnetic stimulation: Applications in neuropsychiatry...
Patients were excluded if they met any of the following criteria: (1) Non-adherence to dietary guidelines, (2) Presence of metabolic syndrome, or (3) Pregnancy. Through use of the randomization software and blocked design, subjects were randomly distributed between the two treatment arms while ...
Given the central role of cellular damage in epileptogenesis,65 preventing damaging effects of prolonged hypoperfusion could be helpful for the treatment of epilepsy. It was reported that the number of neutrophils is increased in postictal human blood samples,66,67,68 which might be linked to ...
Treatment of a prolonged epileptic seizure and status epilepticusA prolonged seizure with unconsciousness is a life-threatening emergency situation requiring immediate care.R. Klviinen
The purpose of this review is to provide insight into each BBW received by antiseizure medications and discuss the FDA recommendations for evaluating the drug benefit/risk, and for monitoring parameters before the initiation of and during treatment....
Women of reproductive age who are prescribed topiramate should be informed of the potential risks, and these should be weighed against the benefits and available treatment options.43 ASM duotherapy is common in women with epilepsy who are not free of seizures when taking monotherapy. In our data...
Epilepsy treatment is challenging due to heterogeneous syndromes, different seizure types and higher inter-individual variability. Identification of genetic variants predicting drug efficacy, tolerability and risk of adverse-effects for anti-seizure medications (ASMs) is essential. Here, we assessed the cli...
Scottish Intercollegiate Guidelines Network (SIGN) recommends prophylactic ASM treatment only if the patient has had previous myoclonic, absence, or focal seizures; if an EEG shows unequivocal epileptic discharges; if the patient has a congenital neurological deficit or if the patient or physician ...
This is also the single NMDAR patient, who did not become seizure-free; one may hypothesize that the long delay in establishing the diagnosis of AE and initiation of immunosuppressant treatment at least in part contributed to the lack of seizure-freedom. Interestingly, both this patient with ...