Objective To compare the clinical efficacy and adverse reactions of first generation antipsychotics(FGA)and second generation antipsychotics(SGA). 目的比较第一代抗精神病药物(FGA)和第二代抗精神病药物(SGA)的临床疗效及不良反应。 2. The development of antipsychotic increases the choices of schizophrenic ph...
The risk is even greater in patients who are taking second-generation antipsychotics (SGAs). SGAs exacerbate metabolic abnormalities and lead to a 3-fold increased risk of severe weight gain, type 2 diabetes, and cardiovascular disease in patients. Mitochondrial dysfunction is ...
Multiple drugs are known to induce metabolic malfunctions, among them second-generation antipsychotics (SGAs). The pathogenesis of such adverse effects is
Second-Generation Antipsychotics (SGAs)doi:10.1007/978-1-4419-1698-3_101220Atypical AntipsychoticsSpringer New YorkSpringer New York
A critical overview of neuroendocrine abnormalities in schizophrenia is provided and the differential impact of different antipsychotics in contributing to neuroendocrine dysfunction is discussed. Introduction Given that the onset of schizophrenia often occurs in adolescence, the role of endocrine abnormalities ...
Second-generation antipsychotics and VTE risk doi:10.1111/ejh.14203European Journal of HaematologyEmma P. DeLoughery
摘要: Background: Studies on therapeutic drug monitoring (TDM) of second-generation antipsychotics (SGAs) have provided conflicting results regarding the association between dose, plasma... 查看全部>>关键词: first-episode antipsychotic agents drug monitoring pharmacokinetics drug effects ...
We searched PubMed for clinical studies that compared first-generation antipsychotics (FGAs; search terms “first-generation antipsychotic”, “conventional antipsychotic”, and “classical antipsychotic”) with second-generation antipsychotics (SGAs, search terms “second-generation antipsychotic”, and “aty...
Cost-effectiveness of second-generation antipsychotics for the treatment of schizophrenia 来自 国家科技图书文献中心 喜欢 0 阅读量: 24 作者:Kuntz,M K.,Park 摘要: Objective To compare the cost-effectiveness of alt 关键词: CATIE cost-effectiveness Markov model schizophrenia second-generation antipsychotics...
It has been suggested that SGAs seem falsely more efficacious than first-generation antipsychotics (FGAs) as a result of reduced efficacy due to use of a high-dose comparator, haloperidol. We performed (1) a meta-analysis of randomized efficacy trials comparing SGAs and FGAs, (2) comparisons ...