In addition, a unique ATF4-responsive sequence within the first intron of the mouse Sec16B gene was characterized. Our study may help to elucidate the regulation of trafficking through the ER鈥揋olgi apparatus and the biogenesis of ER-derived intracellular organelles....
Sec16B was first described as regucalcin gene promoter region-related protein (RGPR-p117) (reviewed in20). Regucalcin is a Ca2+-binding protein that has been shown to exhibit multiple roles within the cell as for example in maintaining intracellular Ca2+ homeostasis, inhibition of protein kinases...
et al. Association of FTO gene polymorphisms and morbid obesity in the population of Extremadura. Endocrinol. Nutr. 57, 203–209 (2010). Article Google Scholar Albuquerque, D., Nóbrega, C. & Manco, L. Association of FTO polymorphisms with obesity and obesity-related outcomes in Portuguese ...
These data suggest SEC16B as a recessive candidate gene for OI.doi:10.15252/emmm.202216834A. El-GazzarBarbara VorabergerF. RauchM. MairhoferKaty SchmidtBrecht GuillemynG. MituloviV. ReitererM. HaunMichaela M MayrEMBO Molecular Medicine
BDNF gene, FAIM2 gene, GNPDA2 gene, Japanese, MC4R gene, obesity, SCE16B gene, TMEM18 geneJournal of Human Genetics, official journal of the Japan Society of Human Genetics, publishes original articles and reviews on all aspects of human genetics, including medical genetics and genomics...
Rs10913469 and rs543874 in SEC16B gene were associated with BMI, and the combined [beta] was 0.04 (95% CI: 0.03-0.05) and 0.03 (95% CI: 0.02-0.04) under additive genetic model, respectively. The two polymorphisms were also associated with the risk of obesity, and the c...