Adipose cells (sebocytes) are described, The invention especially relates to sebaceous gland cells and to a sebaceous gland cell line with the property of being continuously grown over many sub-cultures. The sebocytes are excellently suited for useful applications.ズブリスクリストス...
CELL PROLIFERATION OF THE MOUSE SEBOCYTES IN SKIN AND PREPUTIAL GLAND Claudio Gustavo BARBEITO1,2; Vicente Alberto CATALANO1; Norma Viviana GONZALEZ 3 Preputial glands are specialized sebaceous gland of some rodent as mouse and rat. This gland is regulated by androgens and other hormones. In this...
In this study, SZ95 sebocytes co-cultured with HMel, whether in direct cell contact or with SZ95 sebocytes in inserts, resulted in epidermal HMel flattening with increase in surface area and multiple small dendrites formation. Only in high Ca2+ level and direct cell contact co-culture, the ...
Cell proliferation and lipid synthesis were measured by means of the 4-methylumbelliferyl heptanoate fluorescence assay and nile-red microassay/fluorescence microscopy, respectively. Cells incubated with all hormones mentioned above at f60 showed significantly lower content of sebaceous lipids (P<0.001) vs...
Taken together these data indicate that 13- cis RA causes cell cycle arrest and induces apoptosis in SEB-1 sebocytes by a RAR-independent mechanism, which contributes to its sebosuppressive effect and the resolution of acne. 展开 关键词: Abbreviations: ANOVA, analysis of variance ATRA, all-...
Only in high Ca2+ level and direct cell contact co-culture, the HMel dendrites were remarkably long and preferentially targeted and attached to SZ95 sebocytes. Likewise, only high Ca2+ SZ95 sebocyte conditioned medium stimulated HMel proliferation in a time-dependent manner at days 9 (142.9%, ...
Cell proliferation and lipid synthesis were measured after treatment with GH, IGF-I, 17β-estradiol, DHEA and progesterone. In addition, an interaction between IGF-I and 17β-estradiol signaling pathways was documented. Access through your organization Check access to the full text by signing in ...
Thus, these findings indicate that PM2.5 exerts inhibitory effects on cell proliferation and lipid synthesis, and stimulatory effects on inflammatory cytokine production and AhR signaling activation in human SZ95 sebocytes. 展开 关键词: proliferation cytokine production cell proliferation production synthesis...
We have investigated the expression of known adipogenic factors resistin, galectin-12, sterol response –element-binding protein–1 (SREBP-1) and stearoyl-CoA desaturase in the immortalized sebaceous gland cell line SZ95 and whole skin. Reverse transcriptase-PCR analysis showed the expression of ...
CRH was biologically active on human sebocytes: it induced biphasic increase in synthesis of sebaceous lipids with a maximum stimulation at 10-7M and up-regulated mRNA levels of 3β-hydroxysteroid dehydrogenase/Δ5-4isomerase, although it did not affect cell viability, cell proliferation, or IL-1...