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Methods: Thirty-three people with confirmed MS and 25 matched healthy control subjects (HC) were administered the oral SDMT while eye movements were recorded. Results: Mean SDMT scores were significantly lower in pwMS (p < 0.038). Shorter mean saccade distance in the key area (p = 0.007),...
The Symbol Digit Modalities Test (SDMT) Has Been the Standard Cognitive Measure Used in Multiple Sclerosis (MS) Clinical Trials: How Does It Correlate with... The Symbol Digit Modalities Test (SDMT) Has Been the Standard Cognitive Measure Used in Multiple Sclerosis (MS) Clinical Trials: How ...
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Morrow SA, O'Connor PW, Polman CH, Goodman AD, Kappos L, Lublin FD et al (2010) Evaluation of the symbol digit modalities test (SDMT) and MS neuropsychological screening questionnaire (MSNQ) in natalizumab-treated MS patients over 48 weeks. Mult Scler 16:1385-1392....
Excellent convergent validity was found between the two tests (MS: r = -0.806, p < 0.001 and HC: r = -0.629, p < 0.001). The auto-SDMT had a similar sensitivity and specificity to the traditional oral SDMT in predicting overall impairment on the BICAMS. Conclusion: The auto-SDMT is ...