BackgroundNitric oxide (NO) regulates processes involved in sepsis progression, including vascular and immune function. NO is generated by nitric oxide synthases (NOS) from L-arginine. Cellular L-arginine uptake is inhibited by symmetric dimethylarginine (SDMA) and asymmetric dimethylarginine (ADMA) ...
Mean ADMA serum concentration was significantly higher in patients referred to our hospital either with ongoing mechanical ventilation or without (0.84 ± 0.15 µmol/L and 0.66 ± 0.29 µmol/L, respectively;p = n.s.); it was lowest in primary admissions (0.58 ± 0...