The SDF-1/CXCR4 axis in stem cell preconditioning. Cardiovasc Res 2012;94:400-7. doi:10.1093/cvr/cvs132C. Cencioni, M. C. Capogrossi, and M. Napolitano, "The SDF- 1/CXCR4 axis in stem cell preconditioning," Cardiovascular Research, vol. 94, no. 3, pp. 400-407, 2012....
结论稳定期COPD患者血清SDF-1、CXCR4高表达,与肺功能和CAT评分有关,可为COPD病情判断提供一定参考。 关键词: 肺疾病,慢性阻塞性;趋化因子CXCL12;受体,CXCR4;呼吸功能试验 引用本文 PERMISSIONS Request permissions for this article from CCC. © REQUEST PERMISSIONS 评价本文 确定 放弃 *以上评分为匿名评价 版...
摘㊀要㊀骨髓间充质干细胞（ｍｅｓｅｎｃｈｙｍａｌｓｔｅｍｃｅｌｌｓ，ＭＳＣｓ）具有自我更新和多向分化潜能，在损伤组织修复中起着重要作用㊂基质细胞衍生因子－１（ｓｔｒｏｍａｌｃｅｌｌ⁃ｄｅｒｉｖｅｄｆａｃｔｏｒ⁃１，ＳＤＦ⁃１）／ＣＸＣ趋化因子受体４（ＣＸＣｃｈｅｍｏｋｉｎｅｒｅｃｅｐｔｏｒ４...
根据桂枝加葛根汤的改善血液流变学、扩充血管、调节平滑肌活动等药理作用,并能够明显缓解神经根型颈椎病大鼠的疼痛,目前已将其运用于颈椎病、肩周炎、落枕等临床治疗当中,但其相关的作用机制尚未完全明确。基质细胞衍生因子1(SDF-1)/CXC...
的形成。AMD3100可抑制SDF-1的诱导作用。结论SDF-1/CXCR4轴在内皮祖细胞参与血管新生中可能发挥重 要作用。 关键词:内皮祖细胞;趋化因子SDF-1;血管新生化 中图分类号:R36312 + 1文献标志码:A ActivationofSDF-1/CXCR4axisinducesproliferation,migration, ...
a/CXCR4axis,etc,aswellassomeexistingproblemsinresearchwerediscussed. [Keywords] SDF—la/CXCR4; Cerebralischemiareperfusion; Microvascular generation; Review 缺血性脑血管疾病早期,及时恢复脑缺血区的 Ⅱ液再灌注是目前临床公认的治疗原则。其中,脑 央血再灌注(I/R)后微血管的生成是其治疗中的重 ...
组织损伤部位SD F.I的分泌增加;骨髓中或外周血中CXCR4+的组织定向干细胞沿着SDF—l 浓度梯度迁移到达受损部位,参与组织的修复和重建。SDF.1还能促进损伤部位血管内皮细胞的成血管作用,为组织的修复提供营养支持。文章就SDF.1一CXCR4轴与组织损伤后修复的研究进展进行综述。关键词:基质细胞衍生因子一1;中图分类号:...
关键词 : SDF. 1; CXCR4; 缺血性心脏病; 干细胞治疗 中图分类号 : R541 文献标识码 : A SD F ·-1·-C X C R 4 axis and stem cell therapy of the ischemic heart disease TANG Y i,WEI Y ing-jie, HU Sheng— shou’ , ZHANG Hao ( Research Center for Cardiova scular Regenerative Me...
Vagima Y, Lapid K, Kollet O, Goichberg P, Alon R, Lapidot T 2011. Pathways implicated in stem cell migration: the SDF-1/ CXCR4 axis. Methods Mol Biol 750:277-289.Vagima Y,Lapid K,Kollet O,et al.Pathways implicated in stem cell migration:the SDF-1/CXCR4 axis[J...
The aim of this study was to investigate the effects of the SDF-1/CXCR4 axis on the migration of transplanted BMSCs mobilized by erythropoietin (EPO) toward the lesion site following spinal cord injury (SCI). A model of SCI was established in rats using the modified Allen's test. In...