A composite SSc Damage Index was recently developed by the Scleroderma Clinical Trials Consortium (SCTC-DI) and was demonstrated as a predictor of mortality both in the Australian derivation cohort and in the Canadian validation cohort (1). Several independent predictors of mortality in SSc have ...
The SCTC-DI values inversely correlated to values of 6MWT (r=-0.246, p=0.003). Moreover, the SCTC-DI values correlated inversely with forced vital capacity (r=-0.543, p<0.00000), forced expiratory volume in 1s (r=-0.487, p<0.00000) and diffusion capacity for carbon monoxide (r=-0.484...
Although in pure-SSc there were weak鈥攖o-moderate correlations between the SCTC-DI, age, and disease duration (Spearman's rho:.360-.498;p<0.001), no such associations were found in SSc-overlap patients. Differences in SCTC-DI items in pure-SSc and SSc-overlap are shown in Table 1. ...