Genomic profiling and clinical utility of circulating tumor DNA in metastatic prostate cancer: SCRUM-Japan MONSTAR SCREEN projectCirculating tumor DNA (ctDNA) testing has emerged as a novel tool for cancer precision medicine. This study investigated the genomic profiling and clinical utility of ctDNA ...
We will initiate the 4th stage SCRUM-Japan MONSTAR-SCREEN project as -from genomics to multi-omics with AI- since April 2021, to assess clinical utility for analyzing tissue-based WES, WTS, and Protein analyses as well as circulating tumor NA (nucleic acid) analyses in all solid tumors, uti...
74MO Impact of MTAP loss on prognosis and efficacy of immune check point inhibitors across advanced solid tumors: SCRUM-Japan MONSTAR-SCREEN-1doi:10.1016/j.annonc.2024.08.082K. SeguchiT. FujisawaS. IkedaY. OyamaS. KadowakiC. Morizane
201P Efficacy of antibody drug conjugate (ADC) by mRNA expression of targeted genes in advanced solid tumors: SCRUM-Japan MONSTAR-SCREEN-2doi:10.1016/j.annonc.2024.08.2206T. FujisawaY. NakamuraN. SakamotoT. HashimotoM. NagamineT. Kuwata
733 Background: MONSTAR-SCREEN prospectively assessed the gut microbiota of 2000 patients (pts) with advanced solid cancer at 31 Japanese institutions. Here, we report the interim analysis results of the correlation between gut microbiota and the efficacy of first-line chemotherapy in pts with ...
SCRUM‐Japan GI‐ and MONSTAR‐SCREEN: Path to Realization of Biomarker‐Guided Precision Oncology in Advanced Solid TumorsCirculating tumor DNAMulti-omicsNext generation sequencingPrecision OncologyReal-world datadoi:10.1111/cas.15132Yoshiaki Nakamura...