In this chapter we aim to give insight in the burden of prostate cancer and the effects of early detection and treatments using ample available data from cancer registries and (randomized) clinical trials. Prostate cancer is the leading cancer type in men, and it occurs mainly at age 60鈥 ...
1. National Cancer Institute. Cancer stat facts: prostate cancer. https://seer.cancer.gov/statfacts/html/prost.html. Accessed March 8, 2018. 2. Jahn JL, Giovannucci EL, Stampfer MJ. The high prevalence of undiagnosed prostate cancer at autopsy: implications for epidemiology and treatment of ...
In the absence of RCT of benefit for screening, many now suggest “informed consensus” screening, which encourages a discussion between the patient and his physician with both sides informed of all of the issues. Citation: XU Yang,DONG Birong. Discussion on Screening for Prostate Cancer. ...
It notes that screening with prostate-specific antigen (PSA) blood test aims to reduce death rates from prostate cancer however, it has increased the risk of prostate cancer diagnosis. It further adds that finasteride can lessen the risk of prostate cancer for men who undergo screening.CA: A ...
efforts are now focused on determining the functional underpinnings of these associations. For example, prostate cancer GWASs have been extremely productive, yielding over 100 single-nucleotide polymorphisms (SNPs) with risk association3,4. Importantly, a significant number of these have subsequently been...
In 1995, there will be 244,000 new cases of prostate cancer, and 40,400 deaths from prostate cancer, among men in the United States. The American Cancer Society reports that the incidence rate of prostate cancer is increasing at an accelerated pace, and was 21 percent higher in 1994 than...
Annual PSA screening when used for routine screening in men with previously elevated PSAs or signs or symptoms of disease; PSA testing for men of all ages with signs or symptoms of prostate cancer, and for follow-up of men with prostate cancer; ...
Early Detection of CancerDisease ManagementMaleBackground: Assessment and management of symptoms is a main task in primary care. Symptoms may be defined as 'any subjective evidence of a health problem as perceived by the patient'. In other words, symptoms do not appear as such; symptoms are ...
Estimates of Overdiagnosis of Prostate Cancer Based on Excess Incidence in the Screening Groups of Randomized Controlled Trials eTable 3. Surgical Complications and Perioperative Mortality With Radical Prostatectomy eReferences 1. National Cancer Institute. SEER Cancer Statistics Factsheets: prostate cancer....
In 1990 and 1991 we conducted one-day screens for prostate cancer. This analysis was undertaken to determine the value of the screening procedures for detecting prostate cancer in the community. A total of 579 men, aged 3984 years (mean 58 years), were evaluated by digital rectal examination ...