)# average expression of genes pool#求解基因表达平均值obs_avg = obs_avg[ np.isfinite(obs_avg)#检测数值是否无穷大或小]# Sometimes (and I don't know how) missing data may be there, with nansforn_items =int(np.round(len(obs_avg) / (n_bins -1)))#n个基因/24 进而四舍五入obs_cu...
函数tl.score_genes_cell_cycle用给定S phase 和 G2M phase的两个基因集,计算打分,然后根据得分分配细胞phase, 其源代码在scanpy/tools/_score_genes.py 关于打分细节,见上一篇https://www.yuque.com/huangsh/lq16ea/zbvnce 参数设置: adata: AnnData 对象 s_geneS phase gene list g2m_geneG2M phase ...
Currently the code doesn’t produce the expected number of bins of equal or approximately equal size. Bin 24 is empty when n_bins = 25. The current ranking system code within score_genes() n_items=int(np.round(len(obs_avg)/(n_bins-1)))obs_cut=obs_avg.rank(method="min")//n_item...
IGA score for genes covered by BLACK and YELLOW chromatin.Natalya G. AndreyenkovaTatyana D. KolesnikovaIgor V. MakuninGalina V. PokholkovaLidiya V. BoldyrevaTatyana Yu. ZykovaIgor F. ZhimulevElena S. Belyaeva
We aimed at testing whether a genetic risk score could predict glycemic control and residual β-cell function in type 1 diabetes (T1D). As gene expression may represent an intermediate phenotype between genetic variation and disease, we hypothesized that genes within T1D loci which are expressed ...
The polygenic risk score (PRS) is derived from single nucleotide polymorphisms (SNPs) including those that are genome-wide significant and also including a large number of others more weakly associated with schizophrenia. Such variants are widely dispersed, though concentrated near genes expressed in ...
The Site-Wise Log-Likelihood Score is a Good Predictor of Genes under Positive Selection 来自 NCBI 喜欢 0 阅读量: 110 作者:Huai-Chun,Wang,Edward,Susko,Andrew,J.,Roger 摘要: The strength and direction of selection on the identity of an amino acid residue in a protein is typically measured ...
期刊全称 Genes, Brain and Behavior 6.0 CiteScore 302 过去四年文献总数 1824 过去四年引用总数 85 % 被引用比率 Print ISSN 1601-1848 出版社 Wiley-Blackwell Scopus链接 https://www.scopus.com/sourceid/22138 开放出版 Open Access 否 出版类型
Jasny, Sci Signal, 2008 Powered by This Issue Views 19,338 Citations 124 104 Download PDF More Cite This Permissions Original Investigation January 2018 Association of Polygenic Score for Schizophrenia and HLA Antigen and Inflammation Genes With Response to Lithium in Bipolar Affective DisorderA ...
This study aimed to select the feature genes of hepatocellular carcinoma (HCC) with the Fisher score algorithm and to identify hub genes with the Maximal Clique Centrality (MCC) algorithm. Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (K