485P Heterogeneity and dynamic changes of PD-L1 expression and CPS score in patients with gastroesophageal malignanciesdoi:10.1016/j.annonc.2024.05.397M.E. SalemAtrium Health, Levine Cancer Institute, Charlotte, DC, USAS. WuCaris Life Sciences - Headquarters, Irving, TX, USAJ. Xiu...
该体系包括两个方面,其中临床参数包括呼吸困难(Dyspnea)、厌食症(Anorexia)、卡式功能状态评分(Karnofsky Performance Status,KPS)以及医生临床预测生存期(Clinical Prediction of Survival,CPS);生物学参数包括白细胞计数(Total WBC)、淋巴细胞百分率(Lymphocyte percentage)。评分结果分为3个风险组别, A组30天生存概率>...
Disabled 0 (0.0) 864 (0.5) 1 Values are means ± SDs or frequencies (percentages). CPS-3, Cancer Prevention Study-3; DAS, CPS-3 diet assessment substudy. 2 CPS-3 participants who completed the CPS-3 food frequency questionnaire in 2015; this includes those who participated in the validat...
[C] + cetuximab) improved overall survival (OS) in PD-L1 combined positive score (CPS) ≥20 and CPS ≥1 populations and led to noninferior OS in the total population with favorable safety; first-line P+C vs E had superior OS in CPS ≥20, CPS ≥1, and total populations with ...
Purpose Cancer anorexia-cachexia syndrome (CACS) is common in advanced cancer patients and associated with weight loss, fatigue, impaired quality of life (... JM Salsman,JL Beaumont,K Wortman,... - 《Supportive Care in Cancer》 被引量: 8发表: 2015年 Statin Use and the Progression of Coro...
homolog C isoform 4 SPEG SPEG complex locus ASPM Isoform 1 of Abnormal spindle-like microcephaly- associated protein CPSF1 Cleavage and polyadenylation specificity factor subunit 1 LAMA1 Laminin subunit alpha-1 precursor MYH8 Myosin-8 LCA5L Uncharacterized protein C21orf13 Page ...
结果显示,与低IMS组相比,高IMS组的CD8细胞显著浸润到肿瘤组织的中部,高IMS组可能对PD-1/PD-L1抑制剂有反应(图6.a-b)。利用PD-L1抑制剂治疗的胃癌群体PRJEB25780,研究发现PR/CR组的IMS明显高于SD/PD组;同MSI, EBVs和CPS相比,IMS预测免疫治疗反应的效能更好。
Concordance of PD-L1 combined positive score (CPS) analysis between primary gastric cancer and matched peritoneal metastasis.doi:10.1200/JCO.2024.42.16_suppl.e1606816e16068#Background:Peritoneum represents one of the most common metastatic sites of gastroesophageal adenocarcinoma (GEA) and is associated...
Aim Triple negative subtype (TNBC) is an aggressive breast cancer with inferior survival. Pathological CR (pCR) is a good surrogate endpoint for survival among patients receiving neoadjuvant chemotherapy (NACT). We attempted to validate the composite score(CPS) (Jaccqueline et al, J Clin Oncol ...
Methods: Data from 35 patients with combined positive score (CPS) positive R/M HNSCC receiving first line immunotherapy or immunotherapy in association with chemotherapy, from March 2021 to November 2021 were prospectively reviewed. Treg cells, stromal and intratumoral, and LAG3 expression by cancer ...