Scopolamine, although less potent than atropine, has been used frequently in preanesthetic medication for the purpose of inhibiting the secretions of the nose, mouth, pharynx and bronchi and reduces the occurrence of laryngospasm during general anesthesia. Scopolamine is less potent in the decrease of...
Postoperative Nausea and VomitingUsed transdermally for prevention of nausea and vomiting associated with recovery from anesthesia and surgery, but efficacy is equivocal.SurgeryHas been used preoperatively to inhibit salivation and excessive respiratory tract secretions, but use of general anesthetics (e....
Decreases in salivary and bronchial secretions • Some sedative effect (minor) • Anterograde amnesia The latter two effects are unique to scopolamine and form the basis for its use in anesthesia practice.188Unfortunately, scopolamine is also more apt to produce the phenomenon known asemergence de...
Intravenous, oral, and intramuscular administration have similar half-lives of 68.7 ± 1.0, 63.7 ± 1.3, and 69.1 ±8/0 min, respectively. The half-life is greater with subcutaneous administration at 213 min.5 Following removal of the transdermal patch system, scopolamine plasma concentrations ...
controls the absorption process and rate of drug entry into thesystemic circulationover a 72-hour period. It contains 1.5mg of scopolaminebaseand is applied to the skin in the postauricular area. A priming dose of 140µg is incorporated into the adhesive layer to accelerate the patch׳s ...
Post-operative nausea and vomiting: Apply one patch to the hairless area behind the ear the evening before scheduled surgeryCesarean section surgery: Apply one patch to the hairless area behind the ear one hour prior to surgery (to minimize exposure of the newborn)Duration of therapy: Keep patc...
Common (1% to 10%): Pharyngitis Frequency not reported: Asthma syndrome, dyspnea, mild to moderate respiratory tract reactions, reduced bronchial secretions[Ref]Genitourinary Rare (0.01% to 0.1%): Urinary retention Frequency not reported: Impaired micturition, micturition difficulty, urinary disorders, ...