[8]Chen Y, Paz-Ares L, Reinmuth N, et al. Impact of Brain Metastases on Treatment Patterns and Outcomes With First-Line Durvalumab Plus Platinum-Etoposide in Extensive-Stage SCLC (CASPIAN): A Brief Report. JTO Clin Res Rep. 2022 Apr 26...
[3]Lukas RV, Gondi V, Kamson DO, Kumthekar P, Salgia R. State-of-the-art considerations in small cell lung cancer brain metastases. Oncotarget. 2017; 8(41):71223–33. doi: 10.18632/oncotarget. 19333 [4]Gao, Xinyu et al. “The therapeutic effect of radiotherapy combined with systemic...
[8]Chen Y,Paz-Ares L,Reinmuth N,et al.Impact of Brain Metastases on Treatment Patterns and Outcomes With First-Line Durvalumab Plus Platinum-Etoposide in Extensive-Stage SCLC(CASPIAN):A Brief Report.JTO Clin Res Rep.2022 Apr 26;3(6):100330. *本材料由阿斯利康提供,仅供医疗卫生专业人士进行医...
3.M. Wermke, et al. Phase I Trial of DLL3/CD3 IgG-Like T-Cell Engager BI 764532 in Patients with DLL3-Positive Tumors:Patients with LCNEC. 2024 WCLC Abstract OA10.05. 4.N.J. Choudhury, et al. Impact of Brain Metast...
10.Brown PD, Gondi V, Pugh S, et al. Hippocampal avoidance during whole brain radiotherapy plus memantine for patients with brain metastases: phase III trial NRG Oncology CC001.J Clin Oncol.2020;38:1019-1029. 11.Meyers CA, Rock RP, Fine HA. Refining endpoints in brain tumor clinical tria...
局部增量照射无益于全脑照射SCLC脑转移患者生存再提高脑转移,小细胞肺癌/全脑放射疗法预后Objective To investigate the effect of radiation boost ( Boost ) on further improving overall survival ( OS) and intracranial progression-free survival ( IPFS) of small-cell lung cancer ( SCLC) brain metastases ...
ObjectiveTo investigate the effect of radiation boost (Boost) on further improving overall survival (OS) and intracranial progression-free survival (IPFS) of small-cell lung cancer (SCLC) brain metastases (BM) patients treated by whole-brain radiotherapy (WBRT). MethodsA retrospective analysis of 14...
patients until disease progression or unacceptable toxicity. The trial excluded patients with autoimmune disease, medical conditions requiring systemic immunosuppression, symptomatic interstitial lung disease, or untreated brain metastasis.1Patients with treated brain metastases were eligible if neurologically ...
Contrast‐enhanced MRI of the head was negative for brain metastases Stage IV small-cell lung cancer; ECOG PS 0 Treatment Initiated carboplatin + etoposide + atezolizumab for 4 cycles; followed with atezolizumab as maintenance therapy Follow-up ...
as well as adequate organ function and laboratory tests at baseline. The study permits patients with asymptomatic brain metastases with additional criteria. Also, patients with stable cardiac condition may enroll with a left ventricular ejection fraction ≥40% within ≤21 days of starting the study....