This report presents an in vitro model of TAI employing human induced pluripotent stem cell-derived neurons (hiPSCNs) in a 96 well format with the goal of improving the predictive power and efficiency of pre-clinical drug discovery efforts. hiPSCNs offer unique insight into the pathology of ...
Results Cell classes in human retina To generate a comprehensive cell atlas of human retina, we obtained eight retinas from seven genetically unrelated human donors with no clinical history of ocular disease (TableS1). We dissected foveal (~1.5 mm diameter centered on the foveal pit, which was...
Resources What is the Multi-Attribute Method? The Multi-Attribute Method (MAM) is a peptide mapping based method which takes advantage of high resolution mass spectrometric data. High-resolution mass spectrometry provides the accurate mass information aidi...
A definite version of SAAID1, revised in format and content was created at this final operative phase. National data was combined into the single SAAID1 database. At this time, the dataset went through a third revision, looking for copy and formatting errors, and then the collected data were...
Switching delivery formats can be an effective strategy to enhance they lifecycle of your drug. This whitepaper provides insight into the benefits and challenges of transferring a therapeutic compound from one aseptic injectable format to another, focusing specifically on the following: ...
TheFormatplugin API is architected to support reading and writing of image data in chunks, which provides scalability. It is no longer necessary to have a large quantity of computer RAM to work with large images—SCIFIO reads the data from the source location on demand, paging it into and ...
Section 3 briefly introduces the data format of scientific datasets and the popular distribution-based approaches for handling large-scale scientific datasets, and defines the data-parallel primitives we will use to design our proposed algorithms. The proposed histogram modeling and GMM modeling ...
Import meshes from VTK format, STL, Wavefront OBJ, 3DS, Dolfin-XML, Neutral, GMSH, OFF, PCD (PointCloud), Export meshes as ASCII or binary to VTK, STL, OBJ, PLY ... formats. Analysis tools like Moving Least Squares, mesh morphing and more.. ...
Different bacteria and fungi live as commensal organisms as part of the human microbiota, but shifts to a pathogenic state potentially leading to septic infections commonly occur in immunocompromised individuals. Several studies have reported synergistic
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to ...