Behind The Science Unraveling Parkinson’s Disease Understanding genetic regulators of neurodegeneration Science Briefs Tagged for Degradation Selectively degrading proteins could create new possibilities for patients. Oncology New Frontiers of Cell Therapy Cell therapy is a powerful approach for turning ce...
is the foundation for five of our investigational limb-girdle muscular dystrophy (LGMD) programs. Hear from Dr. Rodino-Klapac about the science behind the LGMDs, the importance of subtype identification and how our gene therapy engine will help engineer potential therapies for this group of inheri...
The Science Behind Gene Doping While gene doping has yet to become a reality, H. Lee Sweeney, a professor of physiology at the University of Pennsylvania School of Medicine and one of the leading researchers in the field of gene therapy, has already been inundated with requests for such dopin...
The subtitle at the beginning was “Catalogs of Autosomal Dominant, Autosomal Recessive, and X-linked Phenotypes.” Although the gene behind the phenotype was always in mind (e.g. the X-linked catalog was created as an indication of the genetic constitution of the X chromosome), almost the ...
(candidate-gene or genome-wide) association analysis studies. The key concepts behind linkage analysis are linkage andlinkage disequilibrium(LD; see Glossary). Once polymorphic markers across the genome of family members have been identified, the estimated logarithm of the odds (LOD) score represents...
February 18, 2025Why do women lag behind in career advancement despite equal ambition? McKinsey’s latest book,The Broken Rung: When the career ladder breaks for women—and how they can succeed in spite of it,reveals the systemic barriers that hinder their first promotion...
CoLab with GSK Life sciences The science behind lower carbon pigs CoLab with the PIC Artificial Intelligence How Industrial AI is boosting sustainability CoLab with Siemens Health Prioritising the global brain health crisis CoLab with Roche Advertisement Download...
FEB 14, 2025 eBooks The Story Behind a Game-Changing Collaboration in Accurate Titration The gold standard in titration requires accurate, high-quality balances integrated into a safe, fast and reliable analyt ... Sponsored By: Sartorius 4 ...
Real innovations in medicine and science are historic and singular; the stories behind each occurrence are precious. At Molecular Medicine we have established the Anthony Cerami Award in Translational Medicine to document and preserve these histories. The monographs recount the seminal events as told in...
The mechanism behind these failures and the large variability of expression in general should be further investigated.12, 23, 26, 29 Integration and oncogenesis after AAV gene therapy? It is assumed that rAAV remain mainly episomal after hepatocyte transduction. However, integration occurs in the ...