耶鲁大学Seth B. Herzon课题组曾在2017年报道了(+)-pleuromutilin(1)和12-epi-pleuromutilin(2)的全合成(Fig. 1b, Science2017, 356, 956)。但该合成路线也存在局限性,包括:1)6参与的Nagata氢氰化反应没有普遍性;2)8和9的偶联反应底物普适性差;3)构建好8元环后再构建C14位季碳立体中心挑战性极大;4)路...
耶鲁大学Seth B. Herzon课题组曾在2017年报道了(+)-pleuromutilin(1)和12-epi-pleuromutilin(2)的全合成(Fig. 1b, Science2017, 356, 956)。但该合成路线也存在局限性,包括:1)6参与的Nagata氢氰化反应没有普遍性;2)8和9的偶联反应底物普适性差;3)构建好8元环后再构建C14位季碳立体中心挑战性极大;4)路...
especially women’s and children’s rights (23,28). Wherever women are empowered educationally, culturally, economically, politically, and legally, fertility rates fall (59). Populations tend to move toward states of zero or negative growth
Science, 356 (6345) (2017), pp. 1362-1369 CrossrefView in ScopusGoogle Scholar IPCC, 2001 IPCC Summary for policy makers J.T. Houghton, Y. Ding, D.J. Griggs, M. Noguer, P.J. van der Linden, X. Dai, K. Maskell, C.A. Johnson (Eds.), Climate Change 2001: the Scientific Basis...
Science, 356 (2017), pp. 493-494, 10.1126/science.aak9521 View in ScopusGoogle Scholar Sippula et al., 2007 O. Sippula, K. Hytönen, J. Tissari, T. Raunemaa, J. Jokiniemi The effect of wood fuel on the emissions from a top-feed pellet stove Energy Fuel., 21 (2007), pp....
(59 quotes) (source) [Barbara McClintock's] burning curiosity, enthusiasm, and uncompromising honesty serve as a constant reminder of what drew us all to science in the first place — Gerald Ralph Fink Obituary, 'Barbara McClintock (1902-1992)' Nature (24 Sep 1992), 272. ...
Science 2017; 356... Single-cell RNA-seq reveals new types of human blood dendritic cells, monocytes, and progenitors. Villani AC, Satija R, Reynolds G et al. Science 2017... G Vitiello 被引量: 0发表: 2017年 Landscape of X chromosome inactivation across human tissues X chromosome ...
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[1] Xiaobing Zhang and Anthony N. van den Pol. Rapid binge-like eating and body weight gain driven by zona incerta GABA neuron activation. Science 356, 853–859 (2017) 同时,谷君也向您推荐生物谷专业的光遗传学盛会,2017光遗传学与疾病研究研讨会将于6月16至17日在上海举行!
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