Variants of the CD44 protein family containing sequences encoded by variant exon 6 (v6) are involved in the metastatic spread of rat and human tumors. The rat-specific antibody I.IASML, which recognizes a v6 epitope, interferes with metastatic dissemination of a rat pancreatic carcinoma. ...
(gene Ⅲ),stem loop structure to the 3′ end of scFv DNA sequence.In this way a naive scFv library for ribosome display was constructed.Results A large naive human scFv library containing 1013 members for ribosome display was successfully constructed.Conclusion The large naive human scFv library...