FBXL4MitophagyNIXPPTC7Mitophagy must be carefully regulated to ensure that cells maintain appropriate numbers of functional mitochondria. The SCFFBXL4 ubiquitin ligase complex suppresses mitophagy by controlling the degradation of BNIP3 and NIX mitophagy receptors, and FBXL4 mutations result in ...
The SKP1-Cul1-F-box and leucine-rich repeat protein 4 (SCF-FbxL4) ubiquitin ligase regulates lysine demethylase 4A (KDM4A)/Jumonji domain-containing 2A (JMJD2A) protein. Van Rechem Capucine,Black Joshua C,Abbas Tarek,Allen Andrew,Rinehart Claire A,Yuan Guo-Cheng,Dutta Anindya,Whetstine ...