Kidney remodelling and scarring: the plasticity of cells. Nephrol Dial Transplant 2003; 18: 1959-1962.El Nahas M. Kidney remodelling and scarring: the plasticity of cells. Nephrol Dial Transplant. 2003;18:1959 -1962.El Nahas M. Kidney remodeling and scarring: the plasticity of cells. ...
University of Sheffield , Sheffield , UK 2 Erwig, Department of Medicine and Therapeutics, University of Introduction The progression of chronic kidney failure remains one of the main challenges in nephrology in view of the ever-increasing number of patients presenting every year with end-stage renal...
This contrasted with a follow-up study published earlier by the same group on two different cohorts in which no impairment of kidney function or increase in hypertension could be found. The present follow-up time was 13 years longer than that of any previous studies. Data on the long-term ...
Role of TGF-β1 in renal parenchymal scarring following childhood urinary tract infection.. Background: Significant variability exists in the outcome of re... Cotton,A Shirley,Gbadegesin,... - 《Kidney International》 被引量: 79发表: 2002年 EPIDEMIOLOGY OF SYMPTOMATIC URINARY TRACT INFECTION IN...
Natural inhibitor of transforming growth factor-β protects against scarring in experimental kidney disease THE central pathological feature of human kidney disease that leads to kidney failure is the accumulation of extracellular matrix in glomeruli. Overexpress... WA Border,NA Noble,T Yamamoto,... ...
Using 99 m Tc-DMSA as the gold standard, MRI had a sensitivity of 100 % and a specificity of 78 % in the diagnosis of a scarred kidney. The concordance in the detection of a scarred zone by post-gadolinium STIR sequence and 99 m Tc-DMSA is 68 %; that by fat-saturated T1-W ...
A new, biodegradable film designed to reduce the severity of scarring following open heart surgery in young children appears to be safe and effective, according to researchers attending the annual meeting of the Society of Thoracic Surgeons in Ft. Lauder
The average number of scars plus or minus standard deviation per scarred kidney was 1.6 +/- 1.5. In 20 renal units the images were contracted and small, possibly due to general scar changes. The average number of renal scars was 0.65 +/- 0.7 in the upper polar zone, 0.52 +/- 0.64 ...
All these results bring up the novel evidence that JQ1 suppresses and reverses corneal scarring through the regulation of BRD4 inhibition and Nrf2-dependant antioxidant induction. Fibrosis is related to many disorders, such as chronic kidney disease, liver cirrhosis, heart failure, idiopathic pulmonary...
We evaluated the protective effects of antioxidant at the onset of fever on renal damage in a rat model of acute pyelonephritis. Twenty rats were allocated to four groups. In groups 1 to 3, the animals were given direct inoculation of Escherichia coli into the right kidney, and group four ...