Common Denominator in Liver Disease: A communication report; Focus on Reversing the Scarring thats Common to Liver DiseasesIndranil CResearch & Reviews
2025 With advanced fibrosis or cirrhosis, liver damage is permanent, but treatment can help prevent further scarring and improve quality of life.54 The most important step in managing liver fibrosis is identifying and treating the condition causing the liver damage. Lindsay Curtis, Health, 8 Apr....
I was admitted to hospital because of stomach pain in July this year, I had a cat scan which showed I had tumours on my adrenal glands. The left being the largest. I am waiting to see the endo surgeon in November but have just finished some tests I’ve blood, 12 hr and 24 hr uri...
The number of patients diagnosed with chronic bile duct disease is increasing and in most cases these diseases result in chronic ductular scarring, necessitating liver transplantation. The formation of ductular scaring affects liver function; however, sc
The inhibitors reduce secretion of several ECM proteins, including collagens, fibrillin and fibronectin in human dermal fibroblasts and in cells obtained from patients with a generalized fibrotic disease (scleroderma). Taken together, targeted interference of the TANGO1-cTAGE5 binding interface could ...
This review is in two sections. The first section summarises 35 conditions, both common and infrequent, causing cicatrising conjunctivitis. Guidelines for making a diagnosis are given together with the use of diagnostic tests, including direct and indire
Several studies have investigated its context-dependent role in visceral fibrosis processes. Shuang et al. found that increased apelin expression levels correlated with the degree of liver fibrosis. Additionally, apelin was shown to increase collagen I (Col1) expression [22]. Meanwhile, other studies...
The most widespread member of this family, transglutaminase-2 (TG2), has a clear fibrogenic role contributing to the stabilisation and accumulation of the ECM consequent to lung, liver, heart and kidney fibrosis4–10. Extracellular TG2 has a number of substrates in the ECM including fibronectin...
All these results bring up the novel evidence that JQ1 suppresses and reverses corneal scarring through the regulation of BRD4 inhibition and Nrf2-dependant antioxidant induction. Fibrosis is related to many disorders, such as chronic kidney disease, liver cirrhosis, heart failure, idiopathic pulmonary...
The present invention relates to use of convertase inhibitors for the reduction of scarring during the healing of wounds and also for reducing fibrosis in the treatment of fibrotic