This was important because doctors prescribe general anti-inflammatory eye drops to be used in the days aftercataract surgeryto prevent pain and damage to the retina. The finding also relates to PCO, as inflammation is known to drivescar tissueformation in other organs. This work opens up the ...
Many axotomised neurons die and none of their severed axons regenerate after penetrant CNS injury in the adult. Debris and necrotic tissue is phagacytosed by hematogenous macrophages and microglia. The scar is formed by astrocytes interacting with fibrou
Financial disclosure: Research support (Dompé); Speakers bureau (Bio-Tissue)NEXT IN THIS ISSUETopics: Eyetube IOL Cataract Surgery Complex Cases Dry Eye Patient Education Astigmatism Management Imaging Technology Presbyopia Astigmatism Surface Procedures News Neuro-Ophthalmology Challenging Cases Refractive Surg...
While this may be partly attributed the lack of a suitable animal model, the research so far has focused on the complex immune responses, with little attention being paid to the local tissue stroma. Previous studies, using conjunctival swabs from patients with trichiasis, have identified a number...
Compared with penetrating keratoplasty or laser surgery, Intacs has the advantage of reshaping the abnormal cornea without removing tissue or injuring the central cornea, which is most critical for clear vision. Studies have shown that Intacs could be easily removed, with reversal of visual, ...
Some scar tissue was left, but it cleared slowly and steadily over the next few years. The induced hyperopia decreased from 5.00 to 1.37 diopters spherical equivalent within 28 months postoperatively. Best corrected visual acuity increased from 20/60 preoperatively to 20/20 at 28 months post...
We defined scar tissue as: disorderly, newly formed collagen fibrils with an accumulation of keratocytes, and haze as the change in corneal transparency seen by the observer as an opacity (caused by backward scatter of light). In a prestudy, one rabbit underwent lasering and was treated (...
Viruses, like Ebola, can stay hidden in our bodies by exploiting a vulnerability in our immune systems. This vulnerability is called "immune privilege," and comes from an old observation that foreign tissue transplanted into certain parts of the body don't elicit the usual immune response. This...
The S58 aptamer is useful in avoiding scar tissue formation, but more research is needed. 10. Conclusions Despite advancements in surgical technique and post-operative care, fibrosis remains a significant obstacle in reducing intraocular pressure after filtering glaucoma surgery. Topical steroids and ...
cornea scarring; regenerative therapy; corneal stromal cells; extracellular matrix; gene therapy; tissue engineering 1. Introduction Various insults to the cornea, including physical injuries, chemical burns, inflammation, and diseases, cause tissue damage leading to a complex cascade of tissue ...