Viruses, like Ebola, can stay hidden in our bodies by exploiting a vulnerability in our immune systems. This vulnerability is called "immune privilege," and comes from an old observation that foreign tissue transplanted into certain parts of the body don't elicit the usual immune response. This...
Direct immunofluorescence (DIF) from perilesional tissue is required to confirm the diagnosis in the immunobullous diseases.19,28Figure 5illustrates the differences between the DIF findings for the intraepithelial ‘pemphigus’ diseases and the subepithelial 'pemphigoid' diseases, first defined by Lever i...
In vivo the epithelium is regularly renewed from a population of relatively undifferentiated cells found in the basal layer of the corneal limbus. The limbus is the narrow ring of tissue located between the cornea and conjunctiva that ends anteriorly at the Bowman's membrane. It supplies physical...