The different capacity for gene silencing reinforces the concept of variability between cells, which confirms on the one hand the importance of carrying out these types of studies in samples isolated from different individuals and, on the other hand, the need to develop a personalized gene editing...
We prepared luciferase plasmids containing wild-type (pYr-MirTarget-homo PTEN 3’UTR) or mutated (pYr-MirTarget-homo PTEN 3’UTR-mut) putative PTEN binding sites for miR-21-5p targeting. HEK-293 cells were first plated in a 6-well plate at 5 × 105cells/well and transfection was o...
physical, and biological characteristics that allow tailored imaging and therapy in the same patient [1]. This personalized approach to nuclear medicine offers the possibility of matching the properties of different theranostic radionuclides with a targeting vector for...
The availability of 43,44𝑔 43,44gSc and 47Sc for clinical studies is still very limited, and their production is mostly undertaken with enriched titanium and calcium target materials. The most common and efficient production of 43Sc and 44𝑔 44gSc proceeds via cyclotrons using low-energy ...
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The availability of 43,44𝑔 43,44gSc and 47Sc for clinical studies is still very limited, and their production is mostly undertaken with enriched titanium and calcium target materials. The most common and efficient production of 43Sc and 44𝑔 44gSc proceeds via cyclotrons using low-energy ...