【摘要】目的 探讨长链非编码RNA SET结合因子2反义RNA1(lncRNA SBF2-AS1)调控miR-372-3p/细胞分裂蛋白激酶6(CDK6)轴对肝癌细胞侵袭及增殖的影响。方法 以Bel7402和SK-hep1细胞为研究对象,上调或下调SBF2-AS1、miR-372-3p及C...
Conclusion LncRNA SBF2-AS1 can positively regulate the expression of CDK6 through miR-372-3p. It can also influence the distribution of cell cycle and affect the proliferation and invasion abilities of hepatocellular carcinoma cells.宋巍徐蓉
Here, we characterized a novel lncRNA, SBF2 antisense RNA 1 (SBF2-AS1), in non-small cell lung cancer (NSCLC). Quantitative real-time PCR was used to quantify SBF2-AS1 expression in NSCLC tissues and cell lines. The correlation of SBF2-AS1 expression with clinicopathologic features was ...
LncRNA SBF2-AS1 has been reported to promote malignant progression in multiple human cancers. However, the roles and underlying mechanisms of SBF2-AS1 in GBM are still unknown. Methods: The levels of SBF-AS1 were identified in GBM tissues and normal brain tissues, and in GBM cell lines and...
High expression of SBF2-AS1 indicates poor survival of LUAD, especially the early-stage LUAD, but not lung squamous cell carcinoma. SBF2-AS1 promotes LUAD cells proliferation in vitro, and RNA-sequencing data shows that many cell-cycle-related genes were downregulated after SBF2-AS1 knockdown...
et al. Correction to: Down-regulated lncRNA SBF2-AS1 inhibits tumorigenesis and progression of breast cancer by sponging microRNA-143 and repressing RRS1. J Exp Clin Cancer Res 39, 60 (2020). https://doi.org/10.1186/s13046-020-01563-5 Download citation Published07 April 2020 DOIhttps://...
lncRNA SBF2-AS1TamoxifenPI3KAKT signalingceRNABreast cancerDRUG-RESISTANCEFACTOR YB-1PROGRESSIONBackgroundY-box binding protein 1 (YBX1) is a multifunctional oncoprotein that can interact with several long non-coding RNAs (lncRNAs) to regulate metastasis in malignancies including breast cancer (BC). ...
Bcl-2的表达(均P<0.05);白芷提取物可显著促进miR-329-3p的表达,而抑制SBF2-AS1的表达(均P<0.05);双荧光素酶报告实验证实SBF2-AS1可靶向结合miR-329-3p并负向调控其表达;SBF2-AS1过表达可逆转白芷提取物对A2780细胞增殖,凋亡的作用.结论白芷提取物可通过调控SBF2-AS1/miR-329-3p轴抑制卵巢癌细胞增殖,促进...
Conclusion: lncRNA SBF2-AS1 promotes EMT of HeLa cells via miR-140-5p/VEGFA axis.方淑芬熊树华黄欧平万玉珍Chinese Journal of Cancer Biotherapy
SBF2-AS1 upregulated the expression level of ZFP91 by sponging miR-188-5p. And the effects of SBF2-AS1 suppression on AML cells progression could be abolished by miR-188-5p inhibitors. Moreover, we found that SBF2-AS1 inhibition reduced tumor growth in vivo. Taken together, our findings ...