However, the Saytzeff rule does not apply in some of the cases. Furthermore, it has been reported that the steric effect during the elimination may also lead to the product obeying the Hofmann rule, as indicated by the increased ratio of 1-/2-olefin. This rule is very useful in ...
Saytzeff rule and Hofmann rule are very important in predicting the end product of an organicelimination reaction. These rules can indicate the nature of the final product of a particular organic chemical reaction, based on the substitution of the final product, e.g. most substituted or least su...