该基因编码一种特异性结合核基质结合区的dna结合蛋白。编码蛋白参与转录调控和染色质重塑该基因缺陷与孤立性腭裂和认知功能障碍有关交替剪接导致编码相同蛋白质的多个转录变体[由RefSeq提供,2010年2月] This gene encodes a DNA binding protein that specifically binds nuclear matrix attachment regions. The encoded pr...
[4]Zarate YA, Kaylor J, Fish J. SATB2-Associated Syndrome. 2017 Oct 12. In: Adam MP, Ardinger HH, Pagon RA, et al., editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993-2020. Available from: ncbi.nlm.nih.gov/books/ ...
编码蛋白参与转录调控和染色质重塑该基因缺陷与孤立性腭裂和认知功能障碍有关交替剪接导致编码相同蛋白质的多个转录变体[由RefSeq提供,2010年2月] This gene encodes a DNA binding protein that specifically binds nuclear matrix attachment regions. The encoded protein is involved in transcription regulation and chro...
We tested for the presence of the copy number of SATB2 gene in a sample of 92 patients with CPO using a quantitative real-time PCR approach. In one patient (1%, 95% CI = 0.2%–6%), a 19 Mb de novo deletion encompassing the SATB2 gene was detected. These results suggest that SAT...
SATB2 (special AT-rich binding protein-2) acts as a transcriptional co-factor and modulates chromatin architecture to regulate gene expression. The purpose of this review was to discuss the pathophysiological roles of SATB2 and assess whether it could be used as a therapeutic target for cancer....
1.Splice variants: Alternative splicing may create different sized proteins from the same gene. 2. Relative charge: The composition of amino acids may affects the charge of the protein. 3. Post-translational modification: Phosphorylation, glycosylation, methylation etc. 4. Post-translation cleavage: ...
Ensembl Gene IDENSG00000119042.18 Ensembl mRNA IDSATB2-206 包装清单: 产品编号产品名称包装 QH35397SHuman SATB2 qPCR Primer Pair1nmol each —说明书1份 保存条件: -20℃保存。建议复溶后进行适当分装,避免反复冻融。 注意事项: PCR扩增产物的长度可能会因基因转录后存在多种剪接形式而有所差异。
DNA-binding protein SATB2 binds to DNA at the nuclear matrix- or scaffold associated regions. It is thought to recognize the sugar-phosphate structure of double-stranded DNA. SATB2 is a transcription factor controlling nuclear gene expression by binding to matrix attachment regions (MARs) o...
SATB2 (SATB Homeobox 2) is a Protein Coding gene. Diseases associated with SATB2 include Glass Syndrome and Satb2-Associated Syndrome. SATB2 encodes a DNA binding protein that specifically binds nuclear matrix attachment regions. The encoded protein is involved in transcription regulation and chromati...
Ensembl Gene IDENSG00000225953.5 Ensembl mRNA IDSATB2-AS1-205 包装清单: 产品编号产品名称包装 QH65237SHuman SATB2-AS1 qPCR Primer Pair1nmol each —说明书1份 保存条件: -20℃保存。建议复溶后进行适当分装,避免反复冻融。 注意事项: PCR扩增产物的长度可能会因基因转录后存在多种剪接形式而有所差异。