13). The weeks following the third wave in South Africa, between 10 October and 15 November 2021, were marked by lower levels of transmission, as indicated by a low incidence of reported COVID-19 cases (100–200 new cases per day) and low (<2%) test positivity rates (Fig. 1a–c)....
Although not directly assessed, household crowding (eg, number of people per room) may be more important for SARS-CoV-2 transmission than the total number of people per household, as has been demonstrated for influenza.96-98 The finding that secondary attack rates were higher to adult contacts...
The occurrence rates for G15S, K90R, M49I, S46F, and V186F mutations among 15,476,050 sequenced SARS-CoV-2 Mpro genes in the Global Initia- tive on Sharing All Influenza Data (GISAID) (accessed Fig. 1 SARS-CoV-2 Mpro inhibitor PF-07304814. PF-07304814 is a ...
We observed a typical binding pattern of compounds with very fast association and fast dissociation rates, producing square shapes of sensorgrams (Fig. 5A– D). This made it hard to determine accurate rate constants, and hence we used steady-state affinity model to determine binding affinity (...
COVID-19 death rates per week per million inhabitants stratified by age and sex for the year 2020. Data are re-plotted from reference [22] The causes of these age-related differences in mortality rates are not yet fully understood. [6] Possible causes likely include the less efficient functi...
The relationship between breastfeeding and reported respiratory and gastrointestinal infection rates in young children. BMC Pediatr. 2019;19:339. Article Google Scholar Maertens K, De Schutter S, Braeckman T, Baerts L, Van Damme P, De Meester I, et al. Breastfeeding after maternal immunisation...
Whereas the per-residue decomposition free energy (ΔGbindresidue) was calculated to elucidate which residues of SARS-CoV-2 Mpro are important for the ligand binding. Both ΔGbind and ΔGbindresidue were performed on 500 frames extracted from the last 20 ns of the MD production phase. It ...
It is customary to use rates per 100,000 individuals for deaths. The assumption was that individuals in counties with high death numbers would know a virus victim and be more inclined towards vaccination [62]. Other variables included in the model were population density and the Surgo COVID-...
The percentage variations of vehicular flow in the four ports, distinguished in the two rates due to passenger cars and heavy vehicles, is shown in Figure 16. Figure 16. Variation of road traffic in the Strait of Messina in 2020. As a result of the actions taken to limit the spread of...
Main Outcomes and Measures Multivariable generalized estimating equation negative-binomial regression models were used to assess associations of monthly rates of hospital-onset SARS-CoV-2 infections per 1000 patient-days (defined as a first positive SARS-CoV-2 test...