Testing for SARS-CoV-2 has attracted a tremendous amount of attention as a tool to manage the ongoing COVID-19 pandemic. Although diagnostic laboratory testing is utilized ubiquitously by physicians and encountered regularly by individuals receiving medical care, several aspects of test interpretation ...
IBD患者应该接种SARS-CoV-2疫苗。 SARS-CoV-2疫苗接种的最佳时机是尽早接种。 包括mRNA疫苗、复制失活载体疫苗、灭活疫苗和重组疫苗在内的SARS-CoV-2疫苗接种对IBD患者都是安全的。 IBD患者不应因为正在接受免疫调节治疗而推迟接种SARS-CoV-2疫苗。 接种SARS...
Further, since N501T, F486L and Y453F fall within the SARS-CoV-2 Spike RBD, we considered their role in receptor binding affinity as putative sites of adaptation to a mink host. The Spike RBD (codon positions 319–54145) provides a critical region for SARS-CoV-2 to attach to host ce...
Development and Evaluation,GRADE)建立的IBD疫苗接种及处理的研究证据列表20-23,合并IBD的COVID-19患者临床结局的系统回顾及大型队列研究17 24-26,社会及国家在妊娠期女性接种SARS-CoV-2疫苗方面的观点27-30,与IBD潜在相关的SARS-CoV-2疫苗综述和已发表的3期临床研究数据5 12 16 31-33。
1.严重急性呼吸综合征冠状病毒2或“sars-cov-2”是一种引起冠状病毒病(covid-19)的病毒株。参见例如戈尔巴伦尼亚(gorbalenya)ae等人,自然微生物学(nature microbiology).5(4):536-544(2020年3月)。需要进行治疗性处理来解决全球大流行病。 附图说明 ...
Knowledge of diagnostic tests for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is still evolving, and a clear understanding of the nature of the tests and interpretation of their findings is important. This Viewpoint describes how to interpret 2 types of diagnostic tests commonly ...
SARS-CoV-2 shares some similarities to the two known coronavirus predecessors that caused severe infections in humans to date, i.e. SARS-CoV and MERS-CoV with 79.5% and 50% sequence identity, respectively [9]. However, the SARS-CoV-2 spike protein displays 10 to 20 times greater affinity...
This systematic review and meta-analysis examines evidence for household transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2),
SARS-CoV-2 emerged in late 2019 and caused a pandemic, whereas the closely related SARS-CoV was contained rapidly in 2003. Here, an experimental set-up is used to study transmission of SARS-CoV and SARS-CoV-2 through the air between ferrets over more tha
The SARS-CoV-2 virus has 5 major protein regions necessary for replication or viral assembly: ORF1ab, spike (S), envelop (E), membrane (M), and nucleocapsid (N) proteins [1]. ORF1ab encodes the non-structural protein (nsp) responsible for viral replication, including the papain-like pr...