The development of SARS-CoV-2 vaccines was initiated in early January 2020 when the sequence of the virus became available and moved at record speed with one Phase I trial already starting in March 2020 and currently more than 180 vaccines in various stages of development. Phase I/II trial ...
vaccine developmentThe COVID-19 pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is still spreading globally. The scientific community is attempting to procure an effective treatment and prevention strategy for COVID-19. A rising number of vaccines for COVID-19 ...
Vaccine development research is necessary for controlling transmission, improving community immunity, and preventingfurther SARS-CoV-2 resurgence. The various approaches to future vaccine development can be broadly classified into either protein subunit, plasmid DNA, mRNA, or viral vaccines....
类似地,MERS-CoV和SARS-CoV-2在S糖蛋白上有35%的同源性(32)。最重要的是,来自SARS-CoV-1和SARS-CoV-2的S糖蛋白的RBD具有高度同源性,并且两者都参与与ACE2的结合(33)。 S糖蛋白在冠状病毒疫苗中的应用 SARS-CoV-1和MERS-CoV...
Vaccine development research is necessary for controlling transmission, improving community immunity, and preventingfurther SARS-CoV-2 resurgence. The various approaches to future vaccine development can be broadly classified into either protein subunit, plasmid DNA, mRNA, or viral vaccines...
快速研发SARS-CoV-2疫苗 疫苗观之一 风城黑鹰编译 冠状病毒病-19（COVID-19）大流行让医疗保健发生了重大变化，这些变化包括公共卫生政策和医学临床实践以及大多数人的生活方式。就疫苗的开发来讲，将通常需要的15至20年时间可能缩短至1至1.5年。COVID-19，这一由严重急性呼吸系统综合症-冠状病毒-2（SARS-CoV-...
新型冠状病毒SARS-CoV-2 Vaccines SARS-CoV-2 Vaccines
SARS-CoV-2 vaccinesvaccine developmentimmune responsesneutralizing antibodiesantibody-dependent enhancementThe COVID-19 pandemic mandates the development of a safe and effective Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) vaccine. This review analyzes the complexities, challenges, and other...
we describe the high mutation rate of RNA viruses and dynamic molecular structures of SARS-CoV-2 variants in several major neutralizing epitopes, trying to answer the question of why universal vaccines are difficult to design. Understanding the biological basis of immune evasion is crucial for combat...
vero细胞中灭活的SARS-CoV-2病毒 其他疫苗方法 潜在限制 结论 补充材料 致谢 作者信息(可选) 道德认可和参与同意 数据和材料的可用性 潜在利益冲突的披露 参考文献 冠状病毒(SARS-CoV-2):潜在疫苗的系统评价(机翻整理) Coronavirus (SARS-CoV-2): a systematic review for potential vaccines Mihir Bhatta,Srij...