席卷全球的新型冠状病毒肺炎(corona virus disease 2019,COVID-19)由一种新型单链RNA冠状病毒引起,该病毒被命名为严重急性呼吸综合征冠状病毒2 (severe acute respiratory syndrome coronavirus 2,SARS-CoV-2)。SARS-CoV-2是一种有包膜的正链单股RNA病毒,与严重急性呼吸综合征冠状病毒1(SARS-CoV-1)和中东呼吸综合...
T cells, is significantly enhanced by a boost vaccination. In addition, vaccination not only induces enhanced reactivity to S from endemic human betacoronaviruses, but also results in significant cross-reactivity to both SARS-CoV-1 and Middle East respiratory syndrome-related coronavirus (MERS-CoV)...
Human coronaviruses have caused two epidemics, severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS), since the 21st century. A recently identified new member of the coronavirus genera, SARS-CoV-2, is responsible for the outbreak of COVID-19 pandemic, from which t...
Aberle SW, Stiasny K, Zoufaly A, Aberle JH, Weseslindtner L. 2021. Assessment of S1, S2 and NCP-specific IgM, IgA, and IgG antibody kinetics in acute SARS-CoV-2 infection by a microarray and twelve other immunoassays. J
抗SARS-CoV-2刺突糖蛋白抗体及其治疗用途.pdf,本申请涉及针对β冠状病毒,诸如严重急性呼吸道综合征冠状病毒2(SARS‑CoV‑2)的中和抗体或其抗原结合片段;编码此类中和抗体或其抗原结合片段的核酸;以及包含此类抗体、抗原结合片段或核酸的混合物及组合物。此类中和抗体
Actualmente en el mercado hay diferentes vacunas frente a SARS-CoV-2 que se recomiendan en pacientes con enfermedad inflamatoria intestinal (EII). No tenemos suficiente evidencia sobre la aceptación de este tipo de vacunas. El objetivo del estudio fue evaluar la aceptación de la vacuna frente...
SARS-CoV-2 es un virus RNA con características peculiares que lo diferencian de sus predecesores SARS-CoV y MERS. Dada sus características estructurales y su patogenia, es capaz de provocar diversas manifestaciones clínicas según avanza la enfermedad. Se ha demostrado que el sistema inmuni...
理解广谱中和性sarbecovirus抗体反应是开发新型疗法针对SARS-CoV-2突变体即未来人畜共患sarbecovirus病毒的关键。近日,一篇发表在国际杂志Science上题为“Antibody-mediated broad sarbecovirus neutralization through ACE2 molecular mimicry”的研究报告中,来自华盛顿大学医学院等机构的科学家们开发了一种新型抗体,其或能...
Here, Dillard and Taft-Benz et al. show in a female mouse model how different adjuvants affect inactivated vaccine-mediated protection against homologous SARS-CoV-2 and heterologous SARS-CoV-1-like coronaviruses. They find that an aluminum hydroxide-adjuvanted vaccine can increase risk of adverse ...
(SARS-CoV). The virus, SARS-CoV-2, belongs to a beta genus of coronaviruses and is the seventh member of human coronaviruses,1,2sharing ~80% sequence similarity to SARS-CoV.3,4Furthermore, the homology of SARS-CoV-2 is over 90% similar to those of coronaviruses from bats and ...