Sarc is common in older adults, but the relationship between sarc and treatment tolerability in older patients (pts) with cancer has not been established. This secondary analysis of our nationwide University of Rochester NCORP Research Base randomized trial examines whether pre-treatment sarc was ...
The required sample size was determined using a single population proportion formula: N = Z21−α/2x (p x [1–p]/d2), where N = required sample size, Z = 95% confidence interval, d = precision, andp = prevalence of sarcopenia in older adults. Research by Sr...
Sarcopenia is rare before age 60, though the process of losing muscle begins decades before that. In addition to the biological changes that are part of the aging process, older adults are likely to have additional risk factors, such as inactivity, a poor diet, and chronic disease, which con...
Recent estimates suggest that the overall prevalence of sarcopenia in older adults can range from 10.0% [2] to 82.1% [3, 4]. In addition, previous studies show that the prevalence of sarcopenia is higher in older women than in older men [5,6,7]. A possible explanation for the higher ...
Sarcopenia is rare before age 60, though the process of losing muscle begins decades before that. In addition to the biological changes that are part of the aging process, older adults are likely to have additional risk factors, such as inactivity, a poor diet, and chronic disease, which con...
On a cellular level, sarcopenic muscle demonstrates reductions in both the size and number of myofibers, with a more pronounced impact on type II fibers [4]. These changes are initiated by factors such as lack ofphysical activityand hormonal shifts in older adults. These factors lead to diminis...
The ongoing "Sarcopenia and Physical fRailty IN older people: multi-componenT Treatment strategies (SPRINTT)" randomized controlled trial (RCT) is testing the efficacy of a multicomponent intervention in the prevention of mobility disability in older adults with physical frailty & sarcopenia (PF&S)....
Falls in older adults are a major cause of injury that may result in fracture, disability, poor quality of life, and death18. Some studies have been conducted to explore the possible association between sarcopenia and the incidence of falls19,20, fall risk21,22, previous falls23, recurrent ...
Screening Accuracy of SARC-F for Sarcopenia in the Elderly: A Diagnostic Meta-Analysis Article 25 September 2020 Long-Term Mortality Risk in Older Adults with Sarcopenia: An 11-Year Prospective Cohort Study Comparing AWGS 2014 and AWGS 2019 Guidelines for Enhanced Clinical Utility and Accurate Ri...
In a meta-analysis of over 2,900 older persons, exercise decreased falls and improved physical and cognitive function (29). For persons with sarcopenia higher intensity resistance exercise is the treatment of choice (30). Neuromuscular electric stimulation (NES) increased muscle mass and improved ...