their tumors could not be relevant to human cancer. (In that era, the universality of many basic life processes was not understood.) At this early period, the nature of cancer was poorly understood and the idea that an infectious agent could cause seemed inconceivable. Lastly, and perhaps mos...
Sarcomas are a group of rare and heterogeneous mesenchymal tumors. Although accounting for 1% of all malignancies in the general population, sarcomas represent the 12–15% of tumors occurring in pediatric age [1]. They represent clinically challenging diseases as most of them display aggressive biolo...
A commitment to improving well-being: now in its 38th year, the Feline Health Center continues its support of outreach and groundbreaking research Richards led investigations into vaccine-associated sarcomas, which were tumors that appeared--rarely but often enough to be worrisome--on the sites wher...
Sarcomas of the bladder occur rarely in adults. As a result, the natural history of these unusual tumors and the best methods of treatment are uncertain. We reviewed our experience with 13 patients presenting between 1970 and 1980 (5 had leiomyosarcoma, 5 had carcinosarcoma and 3 had rhabdomy...
No statistical differences were observed in the degree of humanization between the NSG.Tg(Hu-IL-15) mice prior to receiving no sarcoma cells, non-transduced, and LV/hu-IL-12 transduced sarcoma cells (Supplementary Figures S5a–S5e). Murine tumors were monitored at least weekly, with mouse ...
ATM: functions of ATM kinase and its relevance to Hereditary tumors. Int J Mol Sci. 2022;23(1):523. https://doi.org/10.3390/ijms23010523. Article CAS PubMed PubMed Central Google Scholar Zhou H, Chen H, Cheng C, et al. A quality evaluation of the clinical practice guidelines on ...
HS Developed in TKO Mice is Highly Invasive and Transplantable To evaluate the tumorigenic potential of HS developed in TKO mice, we wished to know whether the tumors spread into multiple organs. We examined six organs, the bone marrow, spleen, lung, skeletal muscle (femoral muscle), liver, ...
Mesenchymal Tumors of the GI Tract JOHN R.GOLDBLUM, inSurgical Pathology of the GI Tract, Liver, Biliary Tract, and Pancreas (Second Edition), 2009 Tumor size. Although sarcomas tend to be larger than benign stromal tumors, there is significant overlap, so size alone cannot be used to distin...
HumansMiceMice, NudeSarcomaUterine NeoplasmsAminoglutethimideEstradiolNandroloneThe biologic effect of estrogen and progesterone in human uterine sarcoma is poorly understood in comparison to that of endometrial adenocarcinoma. In an attempt to elucidate the endocrine status of these tumors, we have ...
et al., Primary osteogenic sarcoma of the femur: a model for the use of preoperative chemotherapy in high risk malignant tumors. Cancer Invest. 1984, 2, 181-192.ROSEN G, CAPARROS B, GROSHEN S, et al.: Primary osteo- genic sarcoma of the femur: a model for the use of preope- ...