SAR443579(SAR'579)是一种具有三重功能的抗CD123 NKp46 x CD16自然杀伤细胞接合器(NKCE)(图1)。2023 ASCO会议上,研究者口头报告了SAR'579在复发/难治性急性髓系白血病(R/R AML)、B细胞急性淋巴细胞白血病(B-ALL)或高危骨髓...
基本信息 药品名称 SAR443579; IPH6101 药品类别 创新药; 生物; 抗体 靶点 natural cytotoxicity receptor 1 (NCR1, NKp46); Fc-gamma RIII (FcγRIII, CD16); interleukin-3 receptor alpha (IL-3Rα, CD123) 作用机制 anti-NKp46/CD16/CD123三特异性抗体 药品简介 -- 研发机构 Innate Pharma...
SAR443579 was well tolerated up to doses of 6000 μg/kg QW with observed clinical benefit in patients with R/R AML. The results are consistent with the predicted favorable safety profile. ASH abstract details: Lacutamab Oral Presentation Publication Number: 185 Title: L...