ELM2-SANT Domain-Containing Scaffolding Protein 1 Regulates Differentiation and Maturation of Cardiomyocytes Derived From Human-Induced Pluripotent Stem Cellsdoi:10.1161/JAHA.124.034816Yu-An LuJiacheng SunLu WangMeimei WangYalin WuGetachew, Anteneh
Cell cycle control of telomere protection and NHEJ revealed by a ts mutation in the DNA-binding domain of TRF2 TRF2 is a component of shelterin, the telomere-specific protein complex that prevents DNA damage signaling and inappropriate repair at the natural ends of ......
The SANT-domain-containing co-repressors SMRT, NCoR and SMRTER interact with Class IHDACsin complexes that are tethered to DNA by transcription factors such as the Notch pathway component CSL andnuclear receptors[43,50]. In the mouse, SMRT and NCoR maintain multipotent neural progenitors and inh...
SANT domains are found in a number of chromatin regulators. They contain approximately 50 amino acids and have high similarity to the DNA binding domain of Myb related proteins. Though some SANT domains associate with DNA others have been found to bind u
The SANT domain: A unique histone-tail-binding module? 2004, Nature Reviews Molecular Cell Biology A protein complex containing the conserved Swi2/Snf2-related ATPase Swr1p deposits histone variant H2A.Z into euchromatin 2004, PLoS Biology View all citing articles on Scopus ...
The Terminal acidic SANT 1 (Tacs1) gene of maize is expressed in tissues containing meristems and encodes an acidic SANT domain similar to some chromatin-remodeling complex proteins. | Marian, CO. and Bass, HW. 2005. Biochim Biophys Acta. 1727: 81-6. PMID: 15716051 Evidence for allosteric...
Deletion analysis revealed that this interaction occurs through a region containing the SANT domain of hMI-ER1. Together, these data reveal a functional role for the SANT domain in the action of co-repressor regulatory factors and suggest that the association of hMI-ER1 with Sp1 represents a ...
Sequence alignment revealed that GbRL2 had high homology with other single SANT/MYB domain containing genes, including the RADIALIS genes in Antirrhinum majus and Bournea leiophylla . Semi-quantitative reverse transcript polymerase chain reaction (RT-PCR) revealed that at seedling stage, GbRL2 was ...
The open-reading frame of PhRL was 288bp, encoding a putative 10.97kDa protein of 95 amino acids. Sequence alignment exhibited that PhRL contained a high conserved SANT/MYB domain. Phylogenetic comparison showed that PhRL was clustered together with AtRL5 and AtRL6 of Arabidopsis. Different from ...
Using an shRNA library screen targeting more than 28,000 genes in a mouse B cell line, we have identified a novel, uncharacterized protein of 82kD (KIAA1841, NM_027860), which we have named SANBR (SANT and BTB domain regulator of CSR), as a negative regulator of CSR. The purified, ...