Using the example of analysis of variance ( ANOVA ), it is shown that methods that usually are applied in the context of variable-oriented research can also be of use in person-oriented research. Specifically, it is shown that ANOVA allows one to compare groups of cases based on their ...
Method: The majority of existing framework comprehension approaches can only help programmers to get familiar with the usage of particular fine-grained API elements of the desired framework such as its classes and methods. Nevertheless, our approach is able to find sample applications that implement ...
The growing need for structure determination of membrane proteins incorporated within their native bilayers calls for the development of novel experimental methods and membrane mimetics for the structure-function studies of these important biological constituents. Solid-state NMR of macroscopically aligned sam...
For proteins where these traditional structure-determination methods fail, any experiment that sheds light on the three-dimensional arrangement of the protein and function-related conformational changes will be of great value for understanding function. Over the past decade, major efforts have been ...
- 《Methods in Molecular Biology》 被引量: 50发表: 2009年 Antitumor activity of a new platinum compound (glycolate-o,o') diammineplatinum (II) (254-S), against non-small cell lung carcinoma grown in a human tumor clonogenic assay system. (Glycolate-o,o') diammineplatinum (II) (254-S...
Folding Kinetics of Staphylococcal Nuclease Studied by Tryptophan Engineering and Rapid Mixing Methods To monitor the development of tertiary structural contacts during folding, a unique tryptophan residue was introduced at seven partially buried locations (... K Maki,C Hong,DA Dolgikh,... - 《Journal...
Solid-state NMR methods for oriented membrane proteins Prog. Nucl. Magn. Reson. Spectrosc, 88-89 (2015), pp. 48-85 View in ScopusGoogle Scholar 8 M. Leninger, N.J. Traaseth NMR spectroscopy approach to study the structure, orientation, and mechanism of the multidrug exporter EmrE Methods...
Well, as you are using JavaScript classes, it’s natural that at some point, as an object-oriented programmer, you will feel the need for static methods, such as while trying to implement the singleton pattern, adding a static constructor, helper function, or factory method, etc. Luckily, ...
Methods into Classes 16 Organizing Code to Allow for Easy Changes 16 ix x Creating Classes That Have a Single Responsibility 17 An Example Application: Bicycles and Gears 17 Why Single Responsibility Matters 21 Determining If a Class Has a Single Responsibility 22 Determining When to Make Design ...
The growing need for structure determination of membrane proteins incorporated within their native bilayers calls for the development of novel experimental methods and membrane mimetics for the structure-function studies of these important biological constituents. Solid-state NMR of macroscopically aligned ...