Effect sizes for the power calculation were based on prior work. In a study of 450 men who have sex with men aged 16–20 years old, Garofalo et al. reported the 12-month HIV incidence rate to be between 2.0 and 6.0, with 95% confidence [51]. To be conservative, we assumed a 30%...
Effect sizes for the power calculation were based on prior work. In a study of 450 men who have sex with men aged 16–20 years old, Garofalo et al. reported the 12-month HIV incidence rate to be between 2.0 and 6.0, with 95% confidence [51]. To be conservative, we assumed a 30%...
All data calculation and statistical analysis were performed using R programming (https://www.r-project.org/, version 4.3.0), and the TwoSampleMR package was mainly used for MR analysis [19]. Cochran Q test and leave-one-out analysis were used to evaluate the robustness and reliability of...
2005. A menu-driven facility for complex sample size calculation in randomized controlled trials with a survival or a binary outcome: Update. Stata Journal 5: 123–129. Barthel, F. M.-S., P. Royston, and M. K. B. Parmar. 2009. A menu-driven facility for sample-size calculation in ...
Power and sample size calculation are critical aspects of designing an experiment, whether on humans or on animals. The rigor of the experiment and the ability to reproduce the results of the study rests on the premise that the experiment was adequately powered to detect the effect of interest...
We are grateful to Gordon R. Bernard for his support and to Yuwei Zhu for her assistance in editing this program. Creative Commons License PS: Power and Sample Size Calculation by William D. Dupont is licensed under aCreative Commons Attribution-NonCommercial-NoDerivs 3.0United States License. ...
is developed under the null hypothesis. by pooling data from groups under the null hypothesis, the test statistic is tractable even when an individual cell is zero, as long as all margins are non-zero. for the score test statistic, a corresponding sample size calculation method is as follows...
Full size table Mediation analysis When borderline features were incorporated into the regression analysis, the effect of specific aspects of negative life events on NSSI vanished. This study aimed to investigate the potential explanatory role of borderline traits in the connection between negative life ...
Full size image 4 Discussion In the present study, we applied two-sample Mendelian randomization to causally infer the role of the blood proteome on the risk of head and neck cancer using data from 1927 genetic associations with 1,478 blood proteins. SNPs associated with blood proteome indicators...
This cross-sectional study included 124 adults with early-treated classical PKU from Hungary, Italy, Spain, Switzerland, and Turkey. All participants prospectively completed the PKU quality of life questionnaire (PKU-QoL), a questionnaire specifically designed to evaluate the impact of PKU and its tr...