Evolutionary analysis as a lens for interpreting cancer driver heterogeneity Copy number analysis with Battenberg software showed diploid genomes in all samples (Fig. 5a). A total of 35 putatively oncogenic somatic variants were mapped to the GP5 cancer evolutionary tree (Fig. 5b) [2, 4]. One ...
Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA Robert B West Corresponding author Correspondence to Serafim Batzoglou. Additional information Competing interests SB is a founding advisor of DNAnexus Inc, and member of the Scientific Advisory Boards of 23andMe and ...
Multigene assays for molecular subtypes and biomarkers can aid management of early invasive breast cancer. Using RNA-sequencing we aimed to develop single-sample predictor (SSP) models for clinical markers, subtypes, and risk of recurrence (ROR). A cohor
From a statistical view, the best sample size is one that takes all the data our time, money, support facilities (hospital, pathology lab), and ethics of patient use will permit. Then why all the attention to methods for estimating the minimum sample size required? There are two primary ...
Serial multi-omic analysis of proteome, phosphoproteome, and acetylome provides insights into changes in protein expression, cell signaling, cross-talk and epigenetic pathways involved in disease pathology and treatment. However, ubiquitylome and HLA peptidome data collection used to understand protein degr...
The breast cancer diagnosis was confirmed with a quick pathology report during surgery. This report was thereafter controlled in detail, and the final result was given to the patients two to three weeks later. Women with a confirmed diagnosis of breast cancer were included in the study’s ...
BI-RADS 4 breast lesions are associated with an exceptionally high rate of benign breast pathology and breast cancer, so BI-RADS 4 is subdivided into 4A, 4B and 4C to standardize the risk estimation of breast lesions. The aim of the study: to evaluate the correlation between BI-RADS 4 ...
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Eguiluz et al., “Multitissue array review: a chronological description of tissue array techniques, applications and procedures,” Pathology Research and Practice, 2006, 202(8):561-568. Eldridge et al., “An in vitro selection strategy for conferring protease resistance to ligand binding peptide...
Peripheral nerve analysis is a challenging task for pathologists, given the advent of new diagnoses and techniques of analysis and the impact of molecular ... L Davies - 《Pathology》 被引量: 7发表: 2016年 Intravascular large B-cell lymphoma confirmed by brain biopsy: a case report Intravascula...