Horvitz and Thompson (1952) developed a general theory for construction of unbiased estimates. Regardless of the selection probabilities, as long as they are known and positive it is always possible to construct a useful estimate. Horvitz and Thompson completed the classical theory, and random sampl...
Direct calculations show that the expected value of μˆ is equal to the true value μ, which is expressed by saying that the ML estimate μˆ is unbiased. On the contrary, (1.23)E[σˆ2]=n−1nσ2, showing that σˆ is a biased estimate. ⋄ Example 1.3 The Rayleigh pdf ...
The idea is simply to remove the 𝐵𝑃BP term from the construction of the test. The new test is called the Straightforward Excess Profitability (SEP) test. 4. The Straightforward Excess Profitability Test (SEP) Here, we propose a simple modification of the EP test by removing the 𝐵...
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Construction of the ALE object The sample of gene trees is compacted into an ALE object. This is done using the program ALEobserve. Where geneFamily.treelist is the file containing the sample of gene trees, and 1000 is a number of gene trees that will be discarded. The result of the co...
Construction of pseudo-replicates is one of the key steps in scMerge which later are utilised to estimate the unwanted variation from the data. In scMerge, we proposed a five-step procedure to identify pseudo-replicates by clustering on a mutual nearest cluster (MNC) graph, where each node ...
However, the FMR can still be assessed, since we estimate that the probability that two datasets with different donor annotations may actually share the same true donor is very low. Therefore, we only characterized the ability of NGSCheckmate and Crosscheckfingerprints to accurately classify donor-...
Data preparation for evaluating demultiplexing and the pipeline of HycDemux.ADNA sequence after multi-sample sequencing library construction.BExtract “barcode” sequences (nanopore signals) within sequences (nanopore signals) using a fast heuristic scheme (see the "Materials and methods" section).CCom...
construction of the tenant improvements in the Premises pursuant to the Work Letter (the “Tenant Improvements”); provided, however, that before performing the Tenant Improvements, Landlord shall prepare in good faith an estimated budget for the construction of the Tenant Improvements and deliver ...
In this section, a simplified approach is described for constructing a confidence interval around a point estimate of the pre–post effect size obtained from a single study, given an equal sample size for the pre–post pair (Robey, 2004). Specifically, this simple construction requires nine step...