PCR and sequencing analysis demonstrated that the isolate harbors multiple antibiotic resistance genes, including blaCMY-48 and blaTEM-1B, which mediate resistance to beta-lactam antibiotics, and qnrB6, mediating resistance to quinolone antibiotics.Through multilocus sequence typing, the isolate's ...
FIG. 1B shows the locations of rpsL gene mutations and resulting amino acid changes inS.sp. 12620-H2 (SEQ ID NOs: 1 and 2). FIG. 2 shows the organization of the bifurcated cahuitamycin gene cluster (A) and a proposed biosynthetic pathway of cahuitamycins (B). Domain notation: T, thi...