Here, we show that a human monoclonal antibody with pan-amyloid-binding activity (mAb 3H3) can disrupt biofilms formed by Salmonella enterica serovar Typhimurium in vitro and in vivo. The antibody disrupts the biofilm structure, enhancing biofilm eradication by antibiotics and immune cells. In mice...
Thus, it can be inferred that Salmonella Typhimurium utilizes polyamines, such as spermidine, as a stress response molecule; however, the mechanism remains elusive. Here, we show that spermidine biosynthesis and transport mutants of Salmonella Typhimurium exhibit reduced survival upon infection in RAW264...
typhimurium defective in guanosine 5′-diphosphate-3′-diphosphate (ppGpp) synthesis (ΔppGpp S. typhimurium) induced the infiltration of abundant immune cells in the tumor microenvironment (TME)32,34. The ΔppGpp S. typhimurium (SAM) was engineered to express and secrete therapeutic payloads ...
Urinary Tract Infection Due to Salmonella Typhimurium in a HIV Seropositive Adult Male: A Case ReportA 51 year old male, smoker and alcoholic for the past 20 years presented to medicine OPD with history of urgency, frequency, dysuria and pain in the hypogastric region. He was diagnosed as ...
[1]Each Salmonella subspecies contains multiple serovars.S. enterica subspecies. entericaholds the most serovars and possesses the serovars most significant to human pathology. Some of the most common serovars includeSalmonellaserovarsenteritidis,typhimurium,newport, andjaviana. Serovarstyphiandparatyphi...
Typhoidal strains, includingSalmonellaTyphi andSalmonellaParatyphi A, causetyphoid fever, an invasive disease of humans. Non-typhoidalSalmonellastrains, such asSalmonellaTyphimurium andSalmonellaEnteritidis, causegastroenteritisand are generally limited to the intestine.Salmonellastrains share a core genome with ...
Physiological stressors may alter susceptibility of the host intestinal epithelium to infection by enteric pathogens. In the current study, cytotoxic effect, adhesion and invasion of Salmonella enterica serovar Typhimurium (S. Typhimurium) to Caco-2 cell
Multistate outbreak of Salmonella typhimurium infections associated with eating ground beef--United States, 2004 MMWR Morb Mortal Wkly Rep, 55 (2006), pp. 180-182 Google Scholar [15] A.S. Laufer, J. Grass, K. Holt, J.M. Whichard, P.M. Griffin, L.H. Gould Outbreaks of Salmonella in...
Taylor & Francis Online :: Ozone Inactivation of Pseudomonas aeruginosa, Escherichia coli, Shigella sonnei and Salmonella typhimurium in Water. - Ozone: Sc... (1999). Ozone Inactivation of Pseudomonas aeruginosa, Escherichia coli, Shigella sonnei and Salmonella typhimurium in Water. Ozone: Science &...
For S. Typhimurium isolates, the phage-type DT104 was screened by PCR as previously described [27]. Susceptibility to antimicrobial agents Susceptibility to antimicrobial agents was tested using the disk diffusion method on Mueller-Hinton agar in accord- ance with the CASFM- EUCAST guidelines of ...