Obtain measurements of serum electrolytes, blood urea nitrogen (BUN), creatinine, calcium, magnesium, and glucose. Repeat these tests at least every 12 hours until the salicylate level falls and the acid-base disturbance improves. If hemodialysis is required, testing is needed more frequently. Monit...
Methyl salicylate relieve musculoskeletal pain in the muscles, joints, and tendons by causing irritation and reddening of the skin due to dilated capillaries and increased blood flow. It is pharmacologically similar to aspirin and other NSAIDs but as a topical agent it primarily acts as a rubefaci...
Blood, lymphatic system, Liver, Prostate Species LOAEL Application Route Exposure time Target Organs : Dog : 1 mg/kg : Oral : 12 w : Blood Species NOAEL LOAEL Application Route Exposure time Target Organs Symptoms : Baboon : 0,5 mg/kg : 5 mg/kg : Oral : 52 w : Gastroi...
Blood immunometabolic indices and polymorphonuclear neutrophil function in peripartum dairy cows are altered by level of dietary energy prepartum J. Dairy Sci., 95 (2012), pp. 1749-1758 View PDFView articleGoogle Scholar Guilbault et al., 1987 L.A. Guilbault, W.W. Thatcher, C.J. Wilcox In...
Blood was obtained for determination of Hct and plasma SA, and the rat was exsanguinated. A midline sternotomy was performed, and cannulas were placed in the pulmonary artery and left atrium. The lungs were removed and perfused with 0.9% saline at 15 mL/min in a nonrecirculating manner ...
Abstract MUC1 is a transmembrane mucin that can promote cancer progression, and its upregulation correlates with a worse prognosis in colon cancer. We examined the effects of overexpression of MUC1 in colon cancer cells, finding that it induced epithelial to mesenchymal transition (EMT), including...
is a major human teratogen.23 All subjects were Korean and were assessed as healthy based on a detailed medical examina- tion, which included medical history, blood pressure (BP) and pulse rate (PR) measurements, a 12-lead electrocar- diogram (ECG) test, and clinical laboratory evaluations...
To further examine the molecular mechanism of Zn{[CH3)3C]2Sal}22−against 4T1 cells, RNA-seq analysis was conducted. After Zn{[CH3)3C]2Sal}22−treatment, the expression level of 4965 genes was changed significantly (p < 0.05). Among the abovementioned differentially expressed genes,...
Table 1 Activation of BK channel in the absence and presence of salicylate. Note: Values are expressed as mean ± SEM. Statistical analysis was performed using a paired Student’s two-tailedt-test. Statistical significance was considered at ap-value < 0.05 relative to the control condi...
4049803Augmentation of blood levels of aspirin1977-09-20Cotley et al.424/233 4044125Method of stabilizing acetylsalicylic acid in the presence of d-propoxyphene hydrochloride and compositions thereof1977-08-23Walkleng424/233 3683080COMPOSITIONS FOR INHIBITING ANOMALOUS DEPOSITION AND MOBILIZATION OF CALCIUM...