2021年06月18日,国际学术期刊 Journal for ImmunoTherapy of Cancer 发表了中科院生物物理研究所秦志海课题组关于钙离子结合蛋白S100家族分子S100A4参与肿瘤相关巨噬细胞(TAM)表型转化的重要研究进展,标题为“S100A4 enhances protumour macrophage polarization by control ofPPAR-γ-dependent induction of fatty acid oxid...
所有样品中 PDCD1/PD1的表达都很低,这可解释抗PD1/PDL1抑制剂对GBM的作用功效低的原因。 髓细胞,包括小胶质细胞和骨髓来源的巨噬细胞(Bone Marrow Derived Macrophage,BMDM)在胶质瘤中形成最大的基质区域。作者检出9个具有独特基因表达模式的骨髓亚群(...
In conclusion, S100A4 activates the NF-魏B/NLRP3 inflammasome signaling pathway to promote macrophage pyroptosis induced by Mtb infection. These data provide new insights into how S100A4 affects Mtb-induced macrophage pyroptosis.doi:10.3390/ijms241612709Li, Mengyuan...
pdcd1/pd1的表达都很低,这可解释抗pd1/pdl1抑制剂对gbm的作用功效低的原因. 髓细胞,包括小胶质细胞和骨髓来源的巨噬细胞(bone marrow derived macrophage,bmdm)在胶质瘤中形成最大的基质区域.作者检出9个具有独特基因表达模式的骨髓亚群(mc 1-9).mc1,mc2,mc6和mc7表达先前检出的小胶质细胞标记物p2ry12和tmem...
C1Q labels a highly aggressive macrophage-like leukemia population indicating extramedullary infiltration and relapse Authors - Li-Xue Yang View Article human,mouse IHC,IF Adv Sci (Weinh) Meis1 Targets Protein Tyrosine Phosphatase Receptor J in Fibroblast to Retard Chronic Kidney Disease Progression Auth...
2021年06月18日,国际学术期刊《Journal for ImmunoTherapy of Cancer》发表了中科院生物物理研究所秦志海课题组关于钙离子结合蛋白S100家族分子S100A4参与肿瘤相关巨噬细胞(TAM)表型转化的重要研究进展,标题为"S100A4 enhances protumour macrophage polarization by control of PPAR-γ-dependent induction of fatty acid ...
Macrophages Enhances Colitis-associated Tumorigenesis by Promoting Macrophage Lipid Metabolism Augmented M2 Polarization doi:10.7150/ijbs.98529International Journal of Biological SciencesTing LiuXinyuan ZhangXuanxuan YanLeirong ChengXinlong YanFanxin ZengXue LiZhinan ChenJianchun GuJinhua Zhang...
Li ZH, Dulyaninova NG, House RP, Almo SC, Bresnick AR: S100A4 regulates macrophage chemotaxis. Mol Biol Cell 2010, 21(15):2598–2610. 10.1091/mbc.E09-07-0609 Article PubMed Central CAS PubMed Google Scholar Kim EJ, Helfman DM: Characterization of the metastasis-associated protein, S10...
Also, pro-tumorigenic macrophage marker gene CD206 (Mrc1) and myeloid marker gene CD11b (Itgam) on average was 2.8× and 2.4× higher, respectively, in the metastatic tumors compared to non-metastatic carcinomas. Further, S100a4 and Arsj were among the top overexpressed genes in the ...
BM-Derived Macrophage Culture After being flushed from the femur and tibia from mice, BM cells were incubated in 10 mL of RPMI-1640 medium (Wako) containing 10% heat-inactivated fetal bovine serum (Thermo Fisher Scientific), 100 units/mL penicillin (Thermo Fisher Scientific), 100 μg/mL stre...