The post-translational modification S-sulfenylation functions as a key sensor of oxidative stress. Yet the dynamics of sulfenic acid in proteins remains largely elusive due to its fleeting nature. Here we use single-molecule force-clamp spectroscopy and
S-sulfenylation (S-sulphenylation, or sulfenic acid), the covalent attachment of S-hydroxyl (-SOH) to cysteine thiol, plays a significant role in redox regulation of protein functions. Although sulfenic acid is transient and labile, most of its physiological activities occur under control of S-...
Protein cysteine S-sulfenylation is an essential and reversible post-translational modification that plays a crucial role in transcriptional regulation, stress response, cell signaling and protein function. Studies have shown that S-sulfenylation is involved in many human diseases such as cancer, diabetes...
Preparation of Optically Active Apoverbenone and Verbenone from Nopinone by Use of the Sulfenylation-Dehydrosulfenylation Method. Stability and Reactivity ... Preparation of Optically Active Apoverbenone and Verbenone from Nopinone by Use of the Sulfenylation-Dehydrosulfenylation Method. Stability and ...
Protein S -sulfenylation modulates protein functions, redox homeostasis, various signaling pathways and cellular functions, and is thus associated with many diseases. However, the dynamic nature, transient fate of protein sulfenic acids, and the lack of probes which enable the spatial and temporal prof...
Selective desulfenylation and deselenylation of α-sulfur- and α-seleno-substituted phosphonates under free radical conditions are described. Chemoselectivity and scope of the title reactions were studied using phosphonates additionally functionalized in the α-position by alkyl, phenyl, ethoxy, chloro,...
Potassium iodide promoted thiolation of pyrazolones and benzofurans using aryl sulfonyl chlorides as sulfenylation reagents 喜欢 0 阅读量: 20 作者:Xiaoyu,Zhao,Xia,Chen,Jun,Wei,Aoqi,Kui,Jia,Xiaoliang 摘要: An efficient, transition-metal-free method to synt 关键词:...
This method provided a simple process for the synthesis of β-keto thioethers in moderate to excellent yields. A variety of carbonyl compounds and (hetero)aryl thiols were tolerated in this reaction.关键词: sulfenylation carbonyl compounds hetero)aryl thiols room temperature β-keto thioethers ...