UNII号 08WQ73S7SV 化学名 S-PALMITOYL CYSTEINE 分子式 C19H37NO3S CAS号 114507-35-6 结构式图片 SMILES CCCCCCCCCCCCCCCC(=O)SC[C@H](N)C(O)=O INCHIKEY FRAMWPHPFIXRCP-KRWDZBQOSA-N 别名 L-CYSTEINE, S-(1-OXOHEXADECYL)-;L-CYSTEINE, HEXADECANOATE (ESTER) 扩展信息 ...
S-Palmitoyl cysteinePseAAC5-step ruleStatistical momentsPredictionS-Pahnitoylation is a uniquely reversible and biologically important post-translational modification as it plays an essential role in a variety of cellular processes including signal transduction, protein-membrane interactions, neuronal ...
Using a straightforward mass tag approach, modification of each cysteine residue results in an incremental increase in the mass of the protein. The number of mobility shifts (as detected by western blot analysis) is observed as a ladder of protein bands, each ‘step’ in the ladder representing...
AnkG is S-palmitoylated at cysteine 70. A, endogenous AnkG was immunoprecipitated (IP) from MDCK cell lysates and processed for the biotin switch assay (see “Experimental Procedures”) to detect protein S-acylation. Four major AnkG polypeptides are detected in MDCK cells using an antibody ...
The nonpalmitoylated cysteines in the sample were alkylated with NEM. The cysteines that are blocked by palmitate were not alkylated by NEM. After NEM alkylation, the excess NEM in the samples was removed and hydroxylamine was then used to remove palmitate from palmitoylated proteins and to ...
2) S-[2,3-bis(palmitoyloxy)propyl]-N-palmitoyl cysteine S-[2,3-二(棕榈酰基氧基)丙基]-N-棕榈酰半胱氨酸 3) S benzyl cysteinylglycine S苄基半胱氨酰甘氨酸 4) S-benzyl-cysteinylglycine S-苄基-半胱氨酰甘氨酸 5) cysteinylglycine 半胱氨酰甘氨酸 ...
The wide regulatory affect on this species is endorsed by the presence of 12 proteins containing the conserved DHHC-CRD (DHHC motif within a cysteine-rich domain) that is associated with palmitoyl-transferase activity. Genetic interrogation of these enzymes in Apicomplexa has revealed essentiality and...
After two washes with the urea buffer to remove the reductant, cysteines were blocked by a 20-min incubation with 100 mM MMTS. The filter was then washed three times with the urea buffer and three times with 100 mM TEAB to remove the urea. Digestion was carried out overnight with 4 ...
tryptic peptide library to derive a set of intrinsic size parameters (ISPs) for the palmitoyl (Pal) group (1.26±0.04), carboxyamidomethyl (Am) group (0.92±0.04), and the 20 amino acid residues to assess the influence of Pal- and Am-modification on cysteine and other amino acid residues...
(tert-butylsulfanyl) group for protection of the cysteine side chain since the latter gives rise to quantitative desulfurization during on-resin deprotection.The resulting free thiol function is modified with palmitic acid via a carbo-diimide-mediated coupling and the title compounds are obtained in ...