In multiple SSTR2-expressing SCLC xenograft models, single-dose intravenous RYZ101 3 渭Ci (0.111 MBq) or 4 渭Ci (0.148 MBq) significantly inhibited tumor growth, with deeper responses, including sustained regression, observed in the models with higher SSTR2 levels. The antitumor effect was ...
RYZ101主要用于治疗SSTR2+阳性的固体肿瘤,包括神经内分泌肿瘤(如SSTR阳性胃肠胰腺神经内分泌肿瘤,GEP-NETs)和广泛期小细胞肺癌(ES-SCLC)等。目前,RYZ101用于上述疾病的临床试验已经取得了一定的进展,其中用于SSTR阳性胃肠胰腺神经内分泌肿瘤患者的临床试验已经进入了第三阶段。©...