X-ray structure of full-length human RuvB-Like 2 – mechanistic insights into coupling between ATP binding and mechanical actionRuvB-Like transcription factors function in cell cycle regulation, development and human disease, such as cancer and heart hyperplasia. The mechanisms that regulate adenosine ...
Annie Bouchard1, Denis Faubert1, Benoit Chabot2,3 & Benoit Coulombe1,4 The R2TP/Prefoldin-like (R2TP/PFDL) complex has emerged as a cochaperone complex involved in the assembly of a number of critical protein complexes including snoRNPs, nuclear RNA polymerases and PIKK-containing complexes...
X-ray structure of full-length human RuvB-Like 2 - mechanistic insights into coupling between ATP binding and mechanical actionSurface Charge DistributionATPase CoreHexameric ArrangementSmall-angle X-ray Scattering (SAXS)Electrophoretic Mobility Shift Assay (EMSA)...
Overexpression and role of the ATPase and putative DNA helicase RuvB-like 2 in human hepatocellular carcinoma. Hepatology 46, 1108-1118.Rousseau B, Menard L, Haurie V, Taras D, Blanc J, Moreau-Gaudry F, et al. (2007) Overexpression and role of the ATPase and putative DNA helicase RuvB-...
HIV-1 Exploits the host factor RuvB-like 2 to balance viral protein expression. Cell Host Microbe, 2015, 18: 233-242.Mu X, Fu YJ, Zhu YP, Wang XL, Xuan YF, Shang H, Goff SP, Gao GX. HIV-1 Exploits the host factor RuvB-like 2 to balance viral prot...
Cloutier P, Poitras C, Durand M, Hekmat O, Fiola-Masson E, Bouchard A, Faubert D, Chabot B, Coulombe B (2017) R2TP/Prefoldin-like component RUVBL1/RUVBL2 directly interacts with ZNHIT2 to regulate assembly of U5 small nuclear ribonucleoprotein. Nat Commun 8: 15615...
Chromosomal passenger protein-like staining of RUVBL1/2 during cell division.Christian GentiliDennis CastorSvenja KadenDavid LauterbachMario GysiPatrick SteigemannDaniel W. GerlichJosef JiricnyStefano Ferrari