For decades, rubella, also known as the “German measles,” was considered a mild viral infection of childhood manifesting with fevers, rash, and lymphadenopathy. In the 1940s, the association between rubella infection during pregnancy and devastating fetal effects, including but not limited to hear...
The present live rubella virus vaccine strain licensed for use in the USA is the RA27/3 strain. This strain was first isolated from an infected fetus in the 1960s,78 and further passaged for attenuation through either the WI-38 or MRC-5 human diploid cell lines.79 It is given as a ...
Preblud S, Serdula M, Frank J, et al: Rubella vaccination in the United States: A ten year review. Epidemiol Rev 2: 170–183, 1980 Google Scholar Editor information Editors and Affiliations Rush Medical College, Chicago, Illinois, USA Norbert Gleicher M.D. (Professor of Obstetrics and Gynec...
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Rubella virus was first isolated in tissue culture in 1962 by two research groups, creating the foundation for the development of attenuated rubella virus vaccines. A massive rubella outbreak in the USA that lasted from 1964 to 1965 resulted in an estimated 12·5 million cases of rubella, 20...
Since 1814, when rubella was first described, the origins of the disease and its causative agent, rubella virus (Matonaviridae: Rubivirus), have remained unclear1. Here we describe ruhugu virus and rustrela virus in Africa and Europe, respectively,
Measles, mumps and rubella virus vaccine: Thrombocytopenic purpura in a child: case report
COMMON NAMES: Shepherds purse [USA]; di mi cai, ji cai, hu sheng cao (“life-protecting grass”) [China]; borsa de pastor [Spanish]; borsa di pastore [Italy]; bourse de pasteur [France]; clappedepouch [Ireland]; hirtentasche, hirtenfaschel [Germany]; mother’s heart [Scotland]; pas...
Rubella (German measles) generally is a mild viral illness that may be associated with fever, lymphadenopathy, and a generalized rash. An estimated 50% or more of infections are subclinical. The most serious consequences of rubella occur in infants of women infected early in pregnancy. These infa...
RSV or hepatitis B surface antigens. In some examples, the HIV antigenic insert is a Gag antigenic insert, a gp41 antigenic insert or a gp120 antigenic insert. Also disclosed are uses of the isolated rubella viral vector, such as to induce an immune response to a particular virus, such ...